About: Protein S100-A2     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Protein S100-A2
equivalentClass
OMIM_Number
  • 176993
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Biologically Active Substance
Preferred_Name
  • Protein S100-A2
UMLS_CUI
  • C0388675
Legacy_Concept_Name
  • S100_Calcium_Binding_Protein-A2
FULL_SYN
  • S-100L ProteinSYNCI
  • Protein S100-A2PTNCI
  • CAN19SYNCI
  • S100A2SYNCI
  • S100 Calcium-Binding Protein A2SYNCI
Swiss_Prot
  • P29034
DEFINITION
  • Protein S100-A2 (98 aa, 11 kD) is a cell motility process protein that is encoded by the human S100A2 gene and has a role in endothelial cell migration.NCI
DesignNote
  • Encoded by human S100A2 Gene, 97-amino acid 11 kD S-100L Protein is a member of the S100 Family of cell specific Ca2+-binding proteins containing EF-hand calcium-binding motifs. Induced by growth factors in early G1 and probably by cell-cycle regulation in S phase, S100A2 is preferentially expressed in mammary epithelia and in keratinocytes. S100 proteins are cytoplasmic or nuclear and involved in regulation of cell cycle progression and differentiation. Containing two EF-hand calcium-binding domains, S100 Calcium-Binding Protein A2 interacts with target proteins to link extracellular stimuli to cellular responses and may modulate excess calcium accumulation in mammary epithelial cells. Altered expression of S100A2 has been implicated in breast cancer. (SwissProt and OMIM)
code
  • C21215
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