About: 3-Deazauridine

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	3-Deazauridine
rdfs:subClassOf	Pyrimidine Antagonist Cytidine Triphosphate Synthetase Inhibitor
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Pharmacologic Substance Nucleic Acid, Nucleoside, or Nucleotide
Preferred_Name	3-Deazauridine
NSC_Code	126849
UMLS_CUI	C0000399
CAS_Registry	23205-42-7
FDA_UNII_Code	263CU738ZY
Contributing_Source	FDA
PDQ_Open_Trial_Search_ID	39208
PDQ_Closed_Trial_Search_ID	39208
Chemical_Formula	C10H13NO6
Legacy_Concept_Name	_3-Deazauridine
FULL_SYN	DeazauridineSYNCI 3-DEAZAURIDINEPTFDA263CU738ZY 3-DeazauridinePTNCI 3-DeazauridineSYDTPNSC0126849 2(1H)-pyridinone, 4-hydroxy-1-beta-D-ribofuranosylSNNCI 4-hydroxy-1-(beta-D-ribopentofuranosyl)-2-pyridoneSNNCI
DEFINITION	A synthetic analogue of nucleoside uridine lacking a ring nitrogen in the 3-position. 3-deazauridine inhibits cytidine synthase, thereby reducing intracellular levels of cytidine and deoxycytidine and disrupting DNA and RNA synthesis. This agent may trigger apoptosis and enhance differentiation of neoplastic cells.(NCI04)NCI
code	C193
sameAs	3-Deazauridine
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0023213
is sameAs of	3-Deazauridine

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