About: NF-AT

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	NF-AT
rdfs:subClassOf	Protein or Riboprotein Complex nodeID://b694970 nodeID://b694971 nodeID://b694972 nodeID://b694973 nodeID://b694974 nodeID://b694975 nodeID://b694976
Semantic_Type	Amino Acid, Peptide, or Protein Biologically Active Substance
Preferred_Name	NF-AT
UMLS_CUI	C0288011
Legacy_Concept_Name	NF-AT
FULL_SYN	Nuclear Factor of Activated T-cellsSYNCI NF-ATPTNCI NFAT-1SYNCI
DEFINITION	NFAT is a multi-subunit transcription complex that includes homo- or hetero-dimers of FOS and JUN proteins. NFATC, the Dorsal/Rel family cytosolic component of NFAT, is translocated to the nucleus following TCR-induced PKC stimulation and calmodulin-dependent calcineurin-mediated dephosphorylation. Phosphoprotein NFATP, the 'preexisting component' of NFAT present in the unstimulated T-cell cytosol, locates in the nucleus as part of NFAT after activation.NCI
code	C17903
is someValuesFrom of	nodeID://b697339 nodeID://b697357 nodeID://b697371 nodeID://b697385

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