About: Yeast Artificial Chromosome     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Yeast Artificial Chromosome
rdfs:subClassOf
Semantic_Type
  • Nucleic Acid, Nucleoside, or Nucleotide
Preferred_Name
  • Yeast Artificial Chromosome
UMLS_CUI
  • C0206665
ALT_DEFINITION
  • Chromosomes in which fragments of exogenous DNA ranging in length up to several hundred kilobase pairs have been cloned into yeast through ligation to vector sequences. These artificial chromosomes are used extensively in molecular biology for the construction of comprehensive genomic libraries of higher organisms.MSH2002_06_01
Legacy_Concept_Name
  • Yeast_Artificial_Chromosome
FULL_SYN
  • YACABNCI
  • Yeast Artificial ChromosomePTNCI
  • YAC VectorSYNCI
DEFINITION
  • A cloning vector based upon elements of yeast chromosomes. At a minimum these include: yeast telomeres, a yeast centromere, and a yeast autonomously replicating sequence (ARS). Such vectors are propagated in yeast and then transferred into a target eukaryotic cell where the yeast sequences can be recognized and will maintain the molecule through cell division. These vectors can maintain extremely large amounts of foreign DNA. YACs are maintained as linear moleculesNCI
code
  • C1457
http://linked.open...y/mesh/hasConcept
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