About: Lithium Carbonate     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Lithium Carbonate
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Inorganic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Lithium Carbonate
NSC_Code
  • 16895
UMLS_CUI
  • C0085217
CAS_Registry
  • 554-13-2
FDA_UNII_Code
  • 2BMD2GNA4V
Contributing_Source
  • FDA
ALT_DEFINITION
  • A lithium salt, classified as a mood-stabilizing agent. Lithium ion alters the metabolism of BIOGENIC MONOAMINES in the CENTRAL NERVOUS SYSTEM, and affects multiple neurotransmission systems.MSH2002_06_01
PDQ_Open_Trial_Search_ID
  • 39491
PDQ_Closed_Trial_Search_ID
  • 39491
Chemical_Formula
  • CO3.2Li
Legacy_Concept_Name
  • Lithium_Carbonate
CHEBI_ID
  • CHEBI:6504
FULL_SYN
  • LithaneSYDTPNSC0016895
  • LithobidSYDTPNSC0016895
  • EskalithSYDTPNSC0016895
  • Lithium CarbonatePTNCI
  • LITHIUM CARBONATEPTFDA2BMD2GNA4V
  • LithaneBRNCI
  • LithiumSYNCI
  • LithonateSYDTPNSC0016895
  • LithotabsSYDTPNSC0016895
  • EscalithBRNCI
  • LithobidBRNCI
  • EskalithBRNCI
  • Lithium carbonateSYDTPNSC0016895
  • LithonateBRNCI
  • LithotabsBRNCI
DEFINITION
  • The carbonate salt of lithium, a soft alkali metal, with antimanic and hematopoietic activities. Lithium interferes with transmembrane sodium exchange in nerve cells by affecting sodium, potassium-stimulated adenosine triphosphatase (Na+, K+-ATPase); alters the release of neurotransmitters; affects cyclic adenosine monophosphate (cAMP) concentrations; and blocks inositol metabolism resulting in depletion of cellular inositol and inhibition of phospholipase C-mediated signal transduction. The exact mechanism through which lithium exerts its mood-stabilizing effect has not been established. In addition, lithium stimulates granulocytopoiesis and appears to increase the level of pluripotent hematopoietic stem cells by stimulating the release of hematopoietic cytokines and/or directly acting on hematopoietic stem cells.NCI
code
  • C1318
sameAs
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