About: Variability in concentrations of volatile metabolites emitted by genotypically different strains of Pseudomonas aeruginosa

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Aims: To charactinosa in order to evaluate their potential for use as biomarkers of lung infection in noninvasive breath analysis. Methods and Results: Volatile organic compounds (VOCs) emitted from 36 clinical strains of Ps. aeruginosa (belonging to different multilocus sequence types) cultured in liquid and on solid media were analysed by gas chromatography mass spectrometry (GC-MS) and selected ion flow tube mass spectrometry (SIFT-MS). Several previously identified VOCs were detected, including ethanol, acetone, 2-butanone, 2-pentanone, isoprene, aminoacetophenone, dimethyl sulphide, dimethyl disulphide, dimethyl trisulphide and methyl thiocyanate. Additionally, significant production of 3-methyl-butanone, acetophenone, methylthioacetate and methyl thiobutanoate was observed for the first time in this study. SIFT-MS quantifications of VOCs showed high variability between genotypically distinct strains. Conclusions: The data obtained indicate that the production rates of the volatile biomarkers of. Aims: To charactinosa in order to evaluate their potential for use as biomarkers of lung infection in noninvasive breath analysis. Methods and Results: Volatile organic compounds (VOCs) emitted from 36 clinical strains of Ps. aeruginosa (belonging to different multilocus sequence types) cultured in liquid and on solid media were analysed by gas chromatography mass spectrometry (GC-MS) and selected ion flow tube mass spectrometry (SIFT-MS). Several previously identified VOCs were detected, including ethanol, acetone, 2-butanone, 2-pentanone, isoprene, aminoacetophenone, dimethyl sulphide, dimethyl disulphide, dimethyl trisulphide and methyl thiocyanate. Additionally, significant production of 3-methyl-butanone, acetophenone, methylthioacetate and methyl thiobutanoate was observed for the first time in this study. SIFT-MS quantifications of VOCs showed high variability between genotypically distinct strains. Conclusions: The data obtained indicate that the production rates of the volatile biomarkers of. (en)
Title	Variability in concentrations of volatile metabolites emitted by genotypically different strains of Pseudomonas aeruginosa Variability in concentrations of volatile metabolites emitted by genotypically different strains of Pseudomonas aeruginosa (en)
skos:prefLabel	Variability in concentrations of volatile metabolites emitted by genotypically different strains of Pseudomonas aeruginosa Variability in concentrations of volatile metabolites emitted by genotypically different strains of Pseudomonas aeruginosa (en)
skos:notation	RIV/75010330:_____/12:00009802!RIV13-GA0-75010330
http://linked.open...avai/predkladatel	Státní zdravotní ústav
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(GA203/09/0256)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Musílek, Martin Nemec, Alexandr
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Státní zdravotní ústav, příspěvková organizace
http://linked.open...dnocenehoVysledku	176991
http://linked.open...ai/riv/idVysledku	RIV/75010330:_____/12:00009802
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Pseudomonas aeruginosa; in vitro; genotyping; MLST; GC/MS; SIFT-MS (en)
http://linked.open.../riv/klicoveSlovo	Pseudomonas aeruginosa GC/MS SIFT-MS genotyping in vitro MLST
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[93699150D9B5]
http://linked.open...i/riv/nazevZdroje	Journal of applied microbiology
http://linked.open...in/vavai/riv/obor	EE
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Selected ion flow tube mass spectrometry studies of volatile compounds emited by bacterial cultures
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	113
http://linked.open...iv/tvurceVysledku	Smith, D. Musílek, Martin Nemec, Alexandr Dryahina, K. Shestivska, V. Sovová, K. Španěl, P.
http://linked.open...ain/vavai/riv/wos	000307558800025
issn	1364-5072
number of pages	13 (xsd:int)
http://bibframe.org/vocab/doi	10.1111/j.1365-2672.2012.05370.x
is http://linked.open...avai/riv/vysledek of	Variability in concentrations of volatile metabolites emitted by genotypically different strains of Pseudomonas aeruginosa

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