About: Effect of acute hyperinsulinaemia with and without angiotensin II type 1 receptor blockade on resistin and adiponectin concentrations and expressions in healthy subjects

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About: Effect of acute hyperinsulinaemia with and without angiotensin II type 1 receptor blockade on resistin and adiponectin concentrations and expressions in healthy subjects Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	In healthy subjects, acute hyperinsulinaemia is associated with an increase in plasma resistin independently of ARB, while plasma adiponectin is not influenced by insulin or ARB. The expressions of both resistin and adiponectin in s.c. adipose tissue are stimulated by acute hyperinsulinaemia, whereas losartan attenuates their insulin-stimulated expressions. This suggests a potential effect of losartan on adipokines’ expression In healthy subjects, acute hyperinsulinaemia is associated with an increase in plasma resistin independently of ARB, while plasma adiponectin is not influenced by insulin or ARB. The expressions of both resistin and adiponectin in s.c. adipose tissue are stimulated by acute hyperinsulinaemia, whereas losartan attenuates their insulin-stimulated expressions. This suggests a potential effect of losartan on adipokines’ expression (en) U zdravých jedinců je akutní hyperinzulinémie asociovaná se zvýšenými hladinami plazmatického resistinu nezávisle na receptorů pro angiotensin II, zatímco plazmatický adiponektin není ovlivněn. Exprese resistinu i adiponektinu v podkožní tukové tkáni jsou zvýšeny při akutní hyperinzulinémii, zatímco losartan snižuje jeich inzulinem stimulovanou expresi. Tyto výsledky naznačují na možnou úlohu losartanu při expresi adipokinů (cs)
Title	Effect of acute hyperinsulinaemia with and without angiotensin II type 1 receptor blockade on resistin and adiponectin concentrations and expressions in healthy subjects Effect of acute hyperinsulinaemia with and without angiotensin II type 1 receptor blockade on resistin and adiponectin concentrations and expressions in healthy subjects (en) Účinky akutní hyperinzulinémie s anebo bez blokády receptorů pro angiotensin II typu 1 na koncentrace a expresi resistinu a adiponektinu u zdravých jedinců (cs)
skos:prefLabel	Effect of acute hyperinsulinaemia with and without angiotensin II type 1 receptor blockade on resistin and adiponectin concentrations and expressions in healthy subjects Effect of acute hyperinsulinaemia with and without angiotensin II type 1 receptor blockade on resistin and adiponectin concentrations and expressions in healthy subjects (en) Účinky akutní hyperinzulinémie s anebo bez blokády receptorů pro angiotensin II typu 1 na koncentrace a expresi resistinu a adiponektinu u zdravých jedinců (cs)
skos:notation	RIV/67985823:_____/07:00087602!RIV08-AV0-67985823
http://linked.open.../vavai/riv/strany	437;442
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(NR8821), Z(AV0Z50110509)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2008
http://linked.open...aciTvurceVysledku	Mlejnek, Petr Pravenec, Michal
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fyziologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	418810
http://linked.open...ai/riv/idVysledku	RIV/67985823:_____/07:00087602
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	hyperinsulinemia; losartan; adipokines (en)
http://linked.open.../riv/klicoveSlovo	hyperinsulinemia adipokines losartan
http://linked.open...odStatuVydavatele	DK - Dánské království
http://linked.open...ontrolniKodProRIV	[F335D7AB5121]
http://linked.open...i/riv/nazevZdroje	European Journal of Endocrinology
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...vavai/riv/projekt	Role of renin-angiotensin system in pathophysiology of insulin resistance
http://linked.open...UplatneniVysledku	2007
http://linked.open...v/svazekPeriodika	157
http://linked.open...iv/tvurceVysledku	Kazdová, L. Kopecký, J. Mlejnek, Petr Pravenec, Michal Hill, M. Pelikánová, T. Wohl, P. Klementová, M. Krušinová, E.
http://linked.open...n/vavai/riv/zamer	Výzkum molekulárních a buněčných základů fyziologických a patofyziologických procesů s cílem objasnit mechanismy vzniku závažných onemocnění člověka
issn	0804-4643
number of pages	7 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Effect of acute hyperinsulinaemia with and without angiotensin II type 1 receptor blockade on resistin and adiponectin concentrations and expressions in healthy subjects Effect of acute hyperinsulinaemia with and without angiotensin II type 1 receptor blockade on resistin and adiponectin concentrations and expressions in healthy subjects Effect of acute hyperinsulinaemia with and without angiotensin II type 1 receptor blockade on resistin and adiponectin concentrations and expressions in healthy subjects

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