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  • Práce se zabývá optimalizací metody SPE/HPLC pro stanovení vybraných léčiv.
  • Práce se zabývá optimalizací metody SPE/HPLC pro stanovení vybraných léčiv. (cs)
  • Antibiotics are a large group of pharmaceuticals whose consumption in both human and veterinary medicine is growing annually. Most of these biologically active substances occur in waste or surface waters. Sulfonamides are antimicrobial substances of synthetic origin, known as chemotherapeutics, often classified as a group of antibiotics. The work was focused on the optimization and selection of suitable method for the determination of selected sulfonamides in water samples. The tap water purposely contaminated with four sulfonamides (sulfathiazol, sulfamethoxazole, sulfapyridin, sulfadimidin) was used as a blank sample. Optimization of SPE method (Solid Phase Extraction) included comparing of sample extraction by SPE columns ENVI-18 and Oasis HLB. Extraction efficiency was evaluated within different experimental conditions. Determination of selected sulfonamides concentration is performed by high-performance liquid chromatography (HPLC) with diode array detector (DAD). (en)
Title
  • Optimization of SPE/HPLC method for determination of selected pharmaceuticals (en)
  • Optimalizace metody SPE/HPLC pro stanovení vybraných léčiv
  • Optimalizace metody SPE/HPLC pro stanovení vybraných léčiv (cs)
skos:prefLabel
  • Optimization of SPE/HPLC method for determination of selected pharmaceuticals (en)
  • Optimalizace metody SPE/HPLC pro stanovení vybraných léčiv
  • Optimalizace metody SPE/HPLC pro stanovení vybraných léčiv (cs)
skos:notation
  • RIV/62157124:16270/11:43870318!RIV12-MSM-16270___
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  • Z(MSM6215712402)
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  • 218628
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  • RIV/62157124:16270/11:43870318
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  • HPLC/DAD; SPE; water samples; sulfonamides; pharmaceuticals (en)
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  • [A6CCFB7BFB16]
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  • Brno
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  • Brno
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  • Sborník XIII. konference mladých vědeckých pracovníků s mezinárodní účastí
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  • Stoupalová, Michaela
  • Večerek, Vladimír
  • Vávrová, Milada
  • Járová, Kateřina
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  • Veterinární a farmaceutická univerzita Brno
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  • 978-80-7305-010-8
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  • 16270
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