About: Separation of oxalate, formate and glycolate in human body fluid samples by capillary electrophoresis with contactless conductometric detection

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About: Separation of oxalate, formate and glycolate in human body fluid samples by capillary electrophoresis with contactless conductometric detection Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=3&SID=W2bYGanYR4jbvRdJ9qm&page=1&doc=1
Description	A new method for rapid determination of toxic metabolites after methanol and ethylene glycol intoxication - oxalate, formate and glycolate in various body fluid samples (blood serum, saliva, urine, exhaled breath condensate) by capillary electrophoresis with contactless conductometric detection was developed. A selective separation of the three target analytes from other constituents present in the analyzed biological matrices was achieved in less than 6 min in a fused silica capillary of 25 mu m I.D. using an electrolyte comprising 50 mM L-histidine and 50 mM 2-(N-morpholino)ethanesulfonic acid at pH 6.1. The only sample preparation was dilution with deionized water. The limits of detection were 0.4, 0.6 and 1.3 mu M and limits of quantitation 1.3, 1.9 and 4.2 mu M for oxalate, formate and glycolate, respectively. The method provides a simple and rapid diagnostic test in suspected intoxication and is able to distinguish the ingested liquid, based on its metabolite trace. A new method for rapid determination of toxic metabolites after methanol and ethylene glycol intoxication - oxalate, formate and glycolate in various body fluid samples (blood serum, saliva, urine, exhaled breath condensate) by capillary electrophoresis with contactless conductometric detection was developed. A selective separation of the three target analytes from other constituents present in the analyzed biological matrices was achieved in less than 6 min in a fused silica capillary of 25 mu m I.D. using an electrolyte comprising 50 mM L-histidine and 50 mM 2-(N-morpholino)ethanesulfonic acid at pH 6.1. The only sample preparation was dilution with deionized water. The limits of detection were 0.4, 0.6 and 1.3 mu M and limits of quantitation 1.3, 1.9 and 4.2 mu M for oxalate, formate and glycolate, respectively. The method provides a simple and rapid diagnostic test in suspected intoxication and is able to distinguish the ingested liquid, based on its metabolite trace. (en)
Title	Separation of oxalate, formate and glycolate in human body fluid samples by capillary electrophoresis with contactless conductometric detection Separation of oxalate, formate and glycolate in human body fluid samples by capillary electrophoresis with contactless conductometric detection (en)
skos:prefLabel	Separation of oxalate, formate and glycolate in human body fluid samples by capillary electrophoresis with contactless conductometric detection Separation of oxalate, formate and glycolate in human body fluid samples by capillary electrophoresis with contactless conductometric detection (en)
skos:notation	RIV/00216224:14310/14:00073642!RIV15-MSM-14310___
http://linked.open...avai/riv/aktivita	P S
http://linked.open...avai/riv/aktivity	P(ED1.1.00/02.0068), P(GA13-21919S), S
http://linked.open...iv/cisloPeriodika	January
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Bittová, Miroslava Kubáň, Petr Ďurč, Pavol Foret, František
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	44520
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/14:00073642
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Capillary electrophoresis; Contactless conductivity detection; Toxic metabolites; Methanol intoxication; Ethylene glycol intoxication; Body fluid samples (en)
http://linked.open.../riv/klicoveSlovo	Capillary electrophoresis Body fluid samples Ethylene glycol intoxication Toxic metabolites Contactless conductivity detection Methanol intoxication
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[785BE76E990F]
http://linked.open...i/riv/nazevZdroje	Journal of Chromatography A
http://linked.open...in/vavai/riv/obor	CB
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Central european institute of technology Vývoj neinvazivních metod odběru vzorků a analýzy v point-of-care dignostice biologických materiálů.
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	1325
http://linked.open...iv/tvurceVysledku	Bittová, Miroslava Foret, František Kubáň, Petr Ďurč, Pavol
http://linked.open...ain/vavai/riv/wos	000330256200031
issn	0021-9673
number of pages	6 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.chroma.2013.12.039
http://localhost/t...ganizacniJednotka	14310

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