About: Inhibition of gap-junctional intercellular communication and activation of mitogen-activated protein kinases by cyanobacterial extracts - Indications of novel tumor-promoting cyanotoxins?

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About: Inhibition of gap-junctional intercellular communication and activation of mitogen-activated protein kinases by cyanobacterial extracts - Indications of novel tumor-promoting cyanotoxins? Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Extracts of cyanobacteria (laboratory cultures of Microcystis aeruginosa and Aphanizomenon flos-aquae and water blooms dominated by these species) inhibited GJIC and activated MAPKs in a dose-dependent manner (effective concentrations ranging 0.5-5 mg d.w./mL). Effects were independent of the microcystin content and the strongest responses were elicited by the extracts of Aphanizomenon sp. Extracts of cyanobacteria (laboratory cultures of Microcystis aeruginosa and Aphanizomenon flos-aquae and water blooms dominated by these species) inhibited GJIC and activated MAPKs in a dose-dependent manner (effective concentrations ranging 0.5-5 mg d.w./mL). Effects were independent of the microcystin content and the strongest responses were elicited by the extracts of Aphanizomenon sp. (en)
Title	Inhibition of gap-junctional intercellular communication and activation of mitogen-activated protein kinases by cyanobacterial extracts - Indications of novel tumor-promoting cyanotoxins? Inhibition of gap-junctional intercellular communication and activation of mitogen-activated protein kinases by cyanobacterial extracts - Indications of novel tumor-promoting cyanotoxins? (en)
skos:prefLabel	Inhibition of gap-junctional intercellular communication and activation of mitogen-activated protein kinases by cyanobacterial extracts - Indications of novel tumor-promoting cyanotoxins? Inhibition of gap-junctional intercellular communication and activation of mitogen-activated protein kinases by cyanobacterial extracts - Indications of novel tumor-promoting cyanotoxins? (en)
skos:notation	RIV/00216224:14310/10:00049612!RIV12-GA0-14310___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA524/08/0496), Z(AV0Z60050516), Z(MSM0021622412)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Bláha, Luděk Hilscherová, Klára
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	264001
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/10:00049612
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	GJIC; MAPK; cyanobacteria (en)
http://linked.open.../riv/klicoveSlovo	MAPK cyanobacteria GJIC
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[2F951A3EAEE2]
http://linked.open...i/riv/nazevZdroje	Toxicon
http://linked.open...in/vavai/riv/obor	DN
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Tumor promotional mechanisms of cyanobacterial metabolites
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	55
http://linked.open...iv/tvurceVysledku	Bláha, Luděk Hilscherová, Klára Babica, Pavel Upham, B.
http://linked.open...ain/vavai/riv/wos	000273921500016
http://linked.open...n/vavai/riv/zamer	Struktura, funkce a evoluce biodiversity fotoautotrofních organismů a hub: původ a příčiny jejich proměnlivosti, dynamika populací, společenstev a ekosystémů; využití vybraných výsledků k rozvoji Průhonického parku Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)
issn	0041-0101
number of pages	9 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.toxicon.2009.07.009
http://localhost/t...ganizacniJednotka	14310
is http://linked.open...avai/riv/vysledek of	Inhibition of gap-junctional intercellular communication and activation of mitogen-activated protein kinases by cyanobacterial extracts - Indications of novel tumor-promoting cyanotoxins? Inhibition of gap-junctional intercellular communication and activation of mitogen-activated protein kinases by cyanobacterial extracts - Indications of novel tumor-promoting cyanotoxins?

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