About: Maximum-uncertainty linear discrimination analysis of first-episode schizophrenia subjects

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Recent techniques of image analysis brought the possibility to recognize subjects based on discriminative image features. We performed a magnetic resonance imaging (MRI)-based classification study to assess its usefulness for outcome prediction of first-episode schizophrenia patients (FES). We included 39 FES patients and 39 healthy controls (HC) and performed the maximum-uncertainty linear discrimination analysis (MLDA) of MRI brain intensity images. The classification accuracy index (CA) was correlated with the Positive and Negative Syndrome Scale (PANSS) and the Global Assessment of Functioning scale (GAF) at 1-year follow-up. The rate of correct classifications of patients with poor and good outcomes was analyzed using chi-square tests. MLDA classification was significantly better than classification by chance. Leave-oneout accuracy was 72%. CA correlated significantly with PANSS and GAF scores at the 1-year follow-up. Recent techniques of image analysis brought the possibility to recognize subjects based on discriminative image features. We performed a magnetic resonance imaging (MRI)-based classification study to assess its usefulness for outcome prediction of first-episode schizophrenia patients (FES). We included 39 FES patients and 39 healthy controls (HC) and performed the maximum-uncertainty linear discrimination analysis (MLDA) of MRI brain intensity images. The classification accuracy index (CA) was correlated with the Positive and Negative Syndrome Scale (PANSS) and the Global Assessment of Functioning scale (GAF) at 1-year follow-up. The rate of correct classifications of patients with poor and good outcomes was analyzed using chi-square tests. MLDA classification was significantly better than classification by chance. Leave-oneout accuracy was 72%. CA correlated significantly with PANSS and GAF scores at the 1-year follow-up. (en)
Title	Maximum-uncertainty linear discrimination analysis of first-episode schizophrenia subjects Maximum-uncertainty linear discrimination analysis of first-episode schizophrenia subjects (en)
skos:prefLabel	Maximum-uncertainty linear discrimination analysis of first-episode schizophrenia subjects Maximum-uncertainty linear discrimination analysis of first-episode schizophrenia subjects (en)
skos:notation	RIV/00216224:14110/11:00052818!RIV12-MZ0-14110___
http://linked.open...avai/predkladatel	Lékařská fakulta
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(NS10347), P(NS9893), Z(MSM0021622404)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Češková, Eva Janoušová, Eva Přikryl, Radovan Kašpárek, Tomáš Kašpárek, Tomáš Mareček, Radek Vaníček, Jiří
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Lékařská fakulta
http://linked.open...dnocenehoVysledku	210983
http://linked.open...ai/riv/idVysledku	RIV/00216224:14110/11:00052818
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Schizophrenia; First episode; Classification; Brain morphology (en)
http://linked.open.../riv/klicoveSlovo	Schizophrenia Classification Brain morphology First episode
http://linked.open...odStatuVydavatele	IE - Irsko
http://linked.open...ontrolniKodProRIV	[860B47F25DB2]
http://linked.open...i/riv/nazevZdroje	Psychiatry Research: Neuroimaging
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	7 (xsd:int)
http://linked.open...cetTvurcuVysledku	10 (xsd:int)
http://linked.open...vavai/riv/projekt	Modern pattern recognition methods for image data analysis in neuropsychiatric research Prediction of the outcome of initial phases of schizophrenia using brain morphology
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	191
http://linked.open...iv/tvurceVysledku	Kašpárek, Tomáš Přikryl, Radovan Schwarz, Daniel Češková, Eva Janoušová, Eva Mareček, Radek Fujita, Andre Sato, Joao Ricardo Thomaz, Carlos Eduardo Vaníček, Jiří
http://linked.open...ain/vavai/riv/wos	000288728500004
http://linked.open...n/vavai/riv/zamer	The Internal Organisation and Neurobiological Mechanisms of Functional CNS Systems under Normal and Pathological Conditions
issn	0925-4927
number of pages	8 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.pscychresns.2010.09.016
http://localhost/t...ganizacniJednotka	14110
is http://linked.open...avai/riv/vysledek of	Maximum-uncertainty linear discrimination analysis of first-episode schizophrenia subjects Maximum-uncertainty linear discrimination analysis of first-episode schizophrenia subjects

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