About: Aortic remodelling in Fabry disease

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	To evaluate thoracic aortic dilation in patients with Fabry disease (FD). A cohort of 106 patients with FD (52 males; 54 females) from three European centres were studied. The diameter of the thoracic aorta was assessed at three levels (sinus of Valsalva, ascending aorta, and descending aorta) using echocardiograms and cardiovascular magnetic resonance imaging. Aortic dilation at the sinus of Valsalva was found in 32.7% of males and 5.6% of females; aneurysms were present in 9.6% of males and 1.9% of females. No aortic dilation was observed in the descending aorta. There was no correlation between aortic diameter at the sinus of Valsalva and cardiovascular risk factors. Fabry disease should be considered as a cardiovascular disease that affects the heart and arterial vasculature, including the thoracic aorta. Thus, patients with FD should be closely monitored for the presence, and possible progression and complications of aortic dilation. Clinical Trial Registration: Protocol 101/01. Ethics committee, To evaluate thoracic aortic dilation in patients with Fabry disease (FD). A cohort of 106 patients with FD (52 males; 54 females) from three European centres were studied. The diameter of the thoracic aorta was assessed at three levels (sinus of Valsalva, ascending aorta, and descending aorta) using echocardiograms and cardiovascular magnetic resonance imaging. Aortic dilation at the sinus of Valsalva was found in 32.7% of males and 5.6% of females; aneurysms were present in 9.6% of males and 1.9% of females. No aortic dilation was observed in the descending aorta. There was no correlation between aortic diameter at the sinus of Valsalva and cardiovascular risk factors. Fabry disease should be considered as a cardiovascular disease that affects the heart and arterial vasculature, including the thoracic aorta. Thus, patients with FD should be closely monitored for the presence, and possible progression and complications of aortic dilation. Clinical Trial Registration: Protocol 101/01. Ethics committee, (en)
Title	Aortic remodelling in Fabry disease Aortic remodelling in Fabry disease (en)
skos:prefLabel	Aortic remodelling in Fabry disease Aortic remodelling in Fabry disease (en)
skos:notation	RIV/00064165:_____/10:7890!RIV11-MZ0-00064165
http://linked.open...avai/riv/aktivita	N
http://linked.open...avai/riv/aktivity	N
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Linhart, Aleš Paleček, Tomáš
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Všeobecná fakultní nemocnice v Praze / (nerozlišená součást)
http://linked.open...dnocenehoVysledku	247214
http://linked.open...ai/riv/idVysledku	RIV/00064165:_____/10:7890
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Aorta; Atherosclerosis; Fabry disease; Remodelling; clinical manifestations; aneurysms; recommendations; hypertrophy; dilatation; females; cohort; impact (en)
http://linked.open.../riv/klicoveSlovo	aneurysms dilatation Remodelling Atherosclerosis impact recommendations hypertrophy Aorta females Fabry disease clinical manifestations cohort
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[FB1EB9165CC5]
http://linked.open...i/riv/nazevZdroje	European Heart Journal
http://linked.open...in/vavai/riv/obor	FA
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	31
http://linked.open...iv/tvurceVysledku	Linhart, Aleš Paleček, Tomáš Barbey, Frédéric Brakch, Noureddine Eckhardt, Boris Jeanrenaud, Xavier Juli, Christoph Qanadli, Salah D Rizzo, Elena
http://linked.open...ain/vavai/riv/wos	000274338700019
issn	0195-668X
number of pages	7 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Aortic remodelling in Fabry disease Aortic remodelling in Fabry disease Aortic remodelling in Fabry disease

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