About: Transfer of humoral and cell-mediated immunity via colostrum in pigs

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The first aim of our study was to obtain information on the transmission of antigen-specific antibodies from colostrum to respiratory tract mucosa in piglets. The second aim was to confirm the biological relevance of the presence of lymphocytes in colostrum. Therefore, we performed an experiment in which sows were immunized with a model antigen and their piglets were euthanized at different intervals after birth and colostrum intake. Colostrum, bronchoalveolar lavage fluid and blood samples were collected for serological detection of antigen-specific antibodies. Lymphocytes isolated from peripheral blood and lymphatic tissues of piglets were in vitro activated with the antigen. We found that colostrum-derived antibodies can cross into the respiratory tract mucosa. Furthermore, we found that antigen-specific lymphocytes were detectable in mesenteric lymph nodes and peripheral blood, but very rarely in spleen and tracheobronchial lymph nodes. The first aim of our study was to obtain information on the transmission of antigen-specific antibodies from colostrum to respiratory tract mucosa in piglets. The second aim was to confirm the biological relevance of the presence of lymphocytes in colostrum. Therefore, we performed an experiment in which sows were immunized with a model antigen and their piglets were euthanized at different intervals after birth and colostrum intake. Colostrum, bronchoalveolar lavage fluid and blood samples were collected for serological detection of antigen-specific antibodies. Lymphocytes isolated from peripheral blood and lymphatic tissues of piglets were in vitro activated with the antigen. We found that colostrum-derived antibodies can cross into the respiratory tract mucosa. Furthermore, we found that antigen-specific lymphocytes were detectable in mesenteric lymph nodes and peripheral blood, but very rarely in spleen and tracheobronchial lymph nodes. (en)
Title	Transfer of humoral and cell-mediated immunity via colostrum in pigs Transfer of humoral and cell-mediated immunity via colostrum in pigs (en)
skos:prefLabel	Transfer of humoral and cell-mediated immunity via colostrum in pigs Transfer of humoral and cell-mediated immunity via colostrum in pigs (en)
skos:notation	RIV/00027162:_____/11:#0000748!RIV12-MZE-00027162
http://linked.open...avai/predkladatel	Výzkumný ústav veterinárního lékařství, v.v.i,
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1B44024), P(ED0006/01/01), P(GP524/06/P455), Z(MZE0002716202)
http://linked.open...iv/cisloPeriodika	1-2
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Nechvátalová, Kateřina Faldyna, Martin Levá, Lenka Kudláčková, Hana Hlavová-Babíčková, Karolina
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Výzkumný ústav veterinárního lékařství, v.v.i.
http://linked.open...dnocenehoVysledku	235769
http://linked.open...ai/riv/idVysledku	RIV/00027162:_____/11:#0000748
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	colostrum; KLH; piglets; passive immunity; sows (en)
http://linked.open.../riv/klicoveSlovo	colostrum piglets KLH passive immunity sows
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[F1FC892CF4B2]
http://linked.open...i/riv/nazevZdroje	Veterinary Immunology and Immunopathology
http://linked.open...in/vavai/riv/obor	GJ
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Methods of the efficiency improvement of vaccination procedures in farm animals. Induction of the immune response of the respiratory tract in piglets Center for Advanced Microbiology & Immunology Research in Veterinary Medicine
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	142
http://linked.open...iv/tvurceVysledku	Faldyna, Martin Levá, Lenka Nechvátalová, Kateřina Kudláčková, Hana Hlavová-Babíčková, Karolina
http://linked.open...ain/vavai/riv/wos	000292486400011
http://linked.open...n/vavai/riv/zamer	Animal disease research, prevention and food chain protection
issn	0165-2427
number of pages	6 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Transfer of humoral and cell-mediated immunity via colostrum in pigs Transfer of humoral and cell-mediated immunity via colostrum in pigs

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