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Description
  • The results of spectroscopic imaging (SI) measurements are often presented as metabolic images. If the spectra quality is not sufficient, the calculated concentrations are biased and the metabolic images show an incorrect metabolite distribution. To simplify the quality analysis of spectra measured by SI, an error image, reflecting the accuracy of the computed concentrations, can be displayed along with the metabolite image. In this paper the relevance of Cramer-Rao bounds (CRBs) calculated by the LCModel program to describe errors in estimated concentrations is validated using spectra simulations. The relation between the average CRBs and standard deviations (STD) of metabolite concentrations from 100 simulated spectra for various SNR and line broadening conditions is evaluated. A parameter for calculating error images for metabolite ratios is proposed and an effective way to display error images is shown. The results suggest that the average CRBs are strongly correlated with the standard deviations
  • The results of spectroscopic imaging (SI) measurements are often presented as metabolic images. If the spectra quality is not sufficient, the calculated concentrations are biased and the metabolic images show an incorrect metabolite distribution. To simplify the quality analysis of spectra measured by SI, an error image, reflecting the accuracy of the computed concentrations, can be displayed along with the metabolite image. In this paper the relevance of Cramer-Rao bounds (CRBs) calculated by the LCModel program to describe errors in estimated concentrations is validated using spectra simulations. The relation between the average CRBs and standard deviations (STD) of metabolite concentrations from 100 simulated spectra for various SNR and line broadening conditions is evaluated. A parameter for calculating error images for metabolite ratios is proposed and an effective way to display error images is shown. The results suggest that the average CRBs are strongly correlated with the standard deviations (en)
  • Výsledky spektroskopického zobrazování (SI) jsou často prezentovány jako metabolické obrazy. Pokud kvalita spekter není dostatečná, vypočtené koncentrace jsou nesprávné a metabolické obrazy zobrazují nesprávné rozložení metabolitů. V tomto článku je testováno zda parametr Cramer-Rao bound (CRB) vypočtený programem LCMOdel je schopen popisovat chyby vypočtených koncnetrací. Srovnáním vypočtených CRBs se strandartními odchylkami koncentrací vypočtených ze souboru simulovaných spekter vyplývá, že CRBs lze používat pro popsání chych koncentrací. (cs)
Title
  • Error images for spectroscopic imaging by LCModel using Cramer-Rao bounds
  • Error images for spectroscopic imaging by LCModel using Cramer-Rao bounds (en)
  • Chybové obrazy pro spectroskopické zobrazování pomocí LCModelu s Cramer-Rao bounds (cs)
skos:prefLabel
  • Error images for spectroscopic imaging by LCModel using Cramer-Rao bounds
  • Error images for spectroscopic imaging by LCModel using Cramer-Rao bounds (en)
  • Chybové obrazy pro spectroskopické zobrazování pomocí LCModelu s Cramer-Rao bounds (cs)
skos:notation
  • RIV/00023001:_____/06:00000657!RIV07-MZ0-00023001
http://linked.open.../vavai/riv/strany
  • 1-14
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA309/04/0753), Z(MZ0IKEM2005)
http://linked.open...iv/cisloPeriodika
  • 1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 474418
http://linked.open...ai/riv/idVysledku
  • RIV/00023001:_____/06:00000657
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Spectroscopic imaging; error images; LCModel; Cramer-Rao bounds (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV
  • [BFEB7662282E]
http://linked.open...i/riv/nazevZdroje
  • Magnetic resonance materials in physics, biology and medicine
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 19
http://linked.open...iv/tvurceVysledku
  • Hájek, Milan
  • Škoch, Antonín
  • Jírů, Filip
  • Grodd, Wolfgang
  • Klose, Uwe
http://linked.open...n/vavai/riv/zamer
issn
  • 0968-5243
number of pages
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