About: Terlipressin in the treatment of catecholamine-resistant septic shock     Goto   Sponge   NotDistinct   Permalink

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Description
  • The study investigating new therapeutic approach for catecholamine resistant septic shock in critically ill patients. Study examining mechanism of action of drug - terlipressine in new indication. The study trying to optimise hemodynamic situation in patients with severe sepsis induced organ failures. (en)
  • Studie zkoumající využití nového postupu v léčbě septického šoku resistentního na katecholaminy u kriticky nemocných. Studie pokoušející se o normalizaci hemodynamické situace u pacientů v septickém šoku s orgánovým selháním v důsledku těžké sepse.
Title
  • Terlipressin in the treatment of catecholamine-resistant septic shock (en)
  • Terlipresin v léčbě septického šoku rezistentního na katecholaminy
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  • NR9284
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  • septic_shock; norepinephrine; terlipressine; MODS; MOF; rabbit; rat (en)
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  • Experimental model of septic shock was evolved. Terlipressin WAS NOT EFFECTIVE in shock treatment. No correlation was found between vasopresin level and effect of terlipressin. In advanced shock addition of terlipressin to norepinephrin is not effective. (en)
  • Byl vyvinut experimentální model septického šoku. Terlipressin NEBYL účinný v léčbě šoku. Nebyla nalezena závislost mezi hladinou vasopresinu a odpovědí na terlipressin. Přidání terlipressinu k noradrenalinu nestabilizovalo oběh a nezlepšilo prognózu. (cs)
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  • norepinephrine
  • rabbit
  • MODS
  • MOF
  • terlipressine
  • septic_shock
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