About: A Role of Interleukin 8 and other cytokines in the Pathogenesis of the Heparin- induced Thrombocytopenia     Goto   Sponge   NotDistinct   Permalink

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  • Heparin-induced immune-mediated thrombocytopenia (HIT-II) - possible reactivity of the specific antibody against other minor antigens, such as interleukin -8, neutrophill-activating peptide -2 and their complexes with different types of heparin. Heparin - induced immune-mediated thrombocytopenia (HIT- II) - verification of the possibility to measure serotonin release in patients with HIT- II by high performance liquid chromatography (HPLC) - fluorimetric detection. Heparin-induced immune-mediated thrombocytopenia (HIT-II) - introduction of reliable, sensitive and highly specific diagnostic assays for laboratory confirmation of HIT-II in Czech republic. (en)
  • Imunní heparinem indukovaná trombocytopenie (HIT-II) - ověření možné vazby specifické protilátky i na jiné minoritní antigeny: interleukin 8 (IL-8(, neutrofily aktivující peptid 2 (NAP - 2) a jejich komplexy s jednotlivými druhy heparinů. Imunní heparinem indukovaná trombocytopenie (HIT-II) - ověření dostatečné specifity a sensitivity stanovení uvolněného serotoninu z aktivovaných destiček chromatografickou metodou u pacientů s HIT-II. Imunní heparinem indukovaná trombocytopenie (HIT-II) - zavedení citlivých diagnostických laboratorních testů v ČR, vypracování metodiky k laboratornímu potvrzení syndromu.
Title
  • A Role of Interleukin 8 and other cytokines in the Pathogenesis of the Heparin- induced Thrombocytopenia (en)
  • Úloha interleukinu-8 a dalších cytokinů v patogenezi heparinem indukované trombocytopenie
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  • NI6063
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  • Heparin;thrombocytopenia;thrombosis;antibodies;platelet factor 4;Interleukin -8;Neutrophill acivating peptide (en)
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  • Bylo prokázáno,že komplexy IL-8 a NAP-2 s heparinem se mohou díky strukturální podobnosti s PF4 také uplatnňovat také v patofyziologii HIT,ale pouze okrajově. Zavedením citlivých serologických a funkčních testů je možné zlepšit možnostlaboratorní (cs)
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  • antibodies
  • thrombosis
  • Heparin
  • thrombocytopenia
  • Interleukin -8
  • platelet factor 4
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