About: Verapamil

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Verapamil
rdfs:subClassOf	CALCIUM CHANNEL BLOCKERS nodeID://b722909 nodeID://b722910 nodeID://b722911 nodeID://b722912
Has_Salt_Form	VERAPAMIL HYDROCHLORIDE
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Organic Chemical Pharmacologic Substance
Preferred_Name	Verapamil
UMLS_CUI	C0042523
CAS_Registry	52-53-9
FDA_UNII_Code	CJ0O37KU29
Contributing_Source	FDA
ALT_DEFINITION	A calcium channel blocker that is a class IV anti-arrhythmia agent.MSH2002_06_01
PDQ_Open_Trial_Search_ID	39730
PDQ_Closed_Trial_Search_ID	39730
Chemical_Formula	C27H38N2O4
Legacy_Concept_Name	Verapamil
CHEBI_ID	CHEBI:9948
FULL_SYN	VERAPAMILPTFDACJ0O37KU29 VerapamilPTNCI alpha-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-alpha-(1-methylethyl)benzeneacetonitrileSNNCI
DEFINITION	A phenylalkylamine calcium channel blocking agent. Verapamil inhibits the transmembrane influx of extracellular calcium ions into myocardial and vascular smooth muscle cells, causing dilatation of the main coronary and systemic arteries and decreasing myocardial contractility. This agent also inhibits the drug efflux pump P-glycoprotein which is overexpressed in some multi-drug resistant tumors and may improve the efficacy of some antineoplastic agents. (NCI04)NCI
code	C928
sameAs	VERAPAMIL
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0022608
is someValuesFrom of	nodeID://b662609 nodeID://b662619 nodeID://b666479 nodeID://b666489 nodeID://b667715 nodeID://b667721 nodeID://b721016 nodeID://b721017
is Has_Free_Acid_Or_Base_Form of	VERAPAMIL HYDROCHLORIDE
is sameAs of	VERAPAMIL VERAPAMIL

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