About: Celecoxib

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Celecoxib
rdfs:subClassOf	Cyclooxygenase Inhibitor nodeID://b658213 nodeID://b658214 nodeID://b658215 nodeID://b658216 nodeID://b658217
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Organic Chemical Pharmacologic Substance
Preferred_Name	Celecoxib
NSC_Code	719627
UMLS_CUI	C0538927
CAS_Registry	169590-42-5
Accepted_Therapeutic_Use_For	Acute pain; Familial adenomatous polyposis; Primary dysmenorrhea; Osteoarthritis; Rheumatoid arthritis
In_Clinical_Trial_For	Actinic keratosis; bladder cancer; breast cancer; CEA-positive solid tumors; cervical intraepithelial neoplasia; colorectal cancer; esophageal cancer; Ewings sarcoma; glioblastoma multiforme Head and neck cancer; hepatocellular carcinoma; malignant glioma; non-small cell lung cancer; ovarian epithelial cancer; prevention; prostate cancer; skin cancer; thyroid cancer; unspecified solid tumors
FDA_UNII_Code	JCX84Q7J1L
Contributing_Source	FDA
ALT_DEFINITION	A drug that reduces pain. Celecoxib belongs to the family of drugs called nonsteroidal anti-inflammatory agents. It is being studied in the prevention of cancer.NCI-GLOSS
PDQ_Open_Trial_Search_ID	43023
PDQ_Closed_Trial_Search_ID	43023
Chemical_Formula	C17H14F3N3O2S
Legacy_Concept_Name	Celecoxib
CHEBI_ID	CHEBI:41423
FULL_SYN	CelecoxibPTDCP09260 Benzenesulfonamide, 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-SYDTPNSC0719627 YM 177SYNCI CELECOXIBPTFDAJCX84Q7J1L CELECOXIBSYDTPNSC0719627 4-(5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamideSNNCI SC-58635CNNCI CelebrexBRNCI CelecoxibPTNCI celecoxibPTNCI-GLOSSCDR0000045969
DEFINITION	A nonsteroidal anti-inflammatory drug (NSAID) with a diaryl-substituted pyrazole structure. Celecoxib selectively inhibits cyclo-oxygenase-2 activity (COX-2); COX-2 inhibition may result in apoptosis and a reduction in tumor angiogenesis and metastasis.NCI
code	C1728
sameAs	CELECOXIB CELECOXIB
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0276185
is someValuesFrom of	nodeID://b645863 nodeID://b656614 nodeID://b656616 nodeID://b656620 nodeID://b656718 nodeID://b656722 nodeID://b656726 nodeID://b658219 nodeID://b658221 nodeID://b658230 nodeID://b658232 nodeID://b658235 nodeID://b658238 nodeID://b658239 nodeID://b658241 nodeID://b658243 nodeID://b658248 nodeID://b658249 nodeID://b658255 nodeID://b658256 nodeID://b658258 nodeID://b658260 nodeID://b658262 nodeID://b658266 nodeID://b658268
is sameAs of	CELECOXIB CELECOXIB CELECOXIB

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