About: Genetic analysis of metabolic defects in the spontaneously hypertensive rat

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	A genome screening of the BXH/HXB RI strains revealed QTL significantly associated with insulin resistance, dyslipidemia and blood pressure on chromosome 19. These findings suggest that closely linked genes on chromosome 19, or perhaps even a single gene with pleiotropic effects, influence the clustering of metabolic disturbances in the SHR-BN model A genome screening of the BXH/HXB RI strains revealed QTL significantly associated with insulin resistance, dyslipidemia and blood pressure on chromosome 19. These findings suggest that closely linked genes on chromosome 19, or perhaps even a single gene with pleiotropic effects, influence the clustering of metabolic disturbances in the SHR-BN model (en) Celogenomový skrinink BXH/HXB RI kmenů odhalil QTL asociované s inzulinovou rezistencí, dyslipidemií a krevním tlakem na chromozomu 19. Tyto výsledky naznačují, že geny v těsné vazbě, případně pleiotropní účinky jednoho genu, ovlivňují koincidenci metabolických poruch u SHR-BN modelu (cs)
Title	Genetic analysis of metabolic defects in the spontaneously hypertensive rat Genetic analysis of metabolic defects in the spontaneously hypertensive rat (en) Genetická analýza metabolických defektů u spontánně hypertenzních potkanů (cs)
skos:prefLabel	Genetic analysis of metabolic defects in the spontaneously hypertensive rat Genetic analysis of metabolic defects in the spontaneously hypertensive rat (en) Genetická analýza metabolických defektů u spontánně hypertenzních potkanů (cs)
skos:notation	RIV/67985823:_____/02:00142331!RIV07-AV0-67985823
http://linked.open.../vavai/riv/strany	253;258
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA305/00/1646), P(NB5299), Z(AV0Z5011922)
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2007
http://linked.open...aciTvurceVysledku	Kostka, Vlastimil Musilová, Alena Zídek, Václav Mlejnek, Petr Šimáková, Miroslava Pravenec, Michal Křen, Vladimír
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fyziologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	646934
http://linked.open...ai/riv/idVysledku	RIV/67985823:_____/02:00142331
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	metabolic defects; spontaneously hypertensive rat (en)
http://linked.open.../riv/klicoveSlovo	spontaneously hypertensive rat metabolic defects
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[2308A153FEC2]
http://linked.open...i/riv/nazevZdroje	Mammalian Genome
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	7 (xsd:int)
http://linked.open...cetTvurcuVysledku	15 (xsd:int)
http://linked.open...vavai/riv/projekt	Molecular mapping and positional cloning of genes that are responsible for clustering of cardiovascular risk factors Nutritional and pharmacological interventions in insulin resistance and its complications.
http://linked.open...UplatneniVysledku	2002
http://linked.open...v/svazekPeriodika	13
http://linked.open...iv/tvurceVysledku	Kazdová, L. Křen, Vladimír Mlejnek, Petr Pravenec, Michal Zídek, Václav Šimáková, Miroslava Musilová, Alena Horký, K. Jáchymová, M. Míková, B. Křenová, D. Bílá, V. Kurtz, W. T. St. Lezin, E. Kostka, Vlastimil
http://linked.open...n/vavai/riv/zamer	Investigation of normal and pathological physiology of animals - the clarification of the physiological mechanisms operating in humans in health and disease
issn	0938-8990
number of pages	6 (xsd:int)

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