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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Ceftibuten
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Ceftibuten
UMLS_CUI
  • C0055014
CAS_Registry
  • 97519-39-6
FDA_UNII_Code
  • IW71N46B4Y
Contributing_Source
  • FDA
Chemical_Formula
  • C15H14N4O6S2
Legacy_Concept_Name
  • Ceftibuten
CHEBI_ID
  • CHEBI:3510
FULL_SYN
  • CEFTIBUTENPTFDAIW71N46B4Y
  • CeftibutenPTNCI
DEFINITION
  • A semisynthetic, beta-lactamase-stable, third-generation cephalosporin with antibacterial activity. Ceftibuten binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.NCI
code
  • C61666
sameAs
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