About: Ceftizoxime Sodium     Goto   Sponge   Distinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Ceftizoxime Sodium
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Ceftizoxime Sodium
UMLS_CUI
  • C0282391
CAS_Registry
  • 68401-82-1
FDA_UNII_Code
  • 26337D5X88
Contributing_Source
  • FDA
Chemical_Formula
  • C13H12N5O5S2.Na
Legacy_Concept_Name
  • Ceftizoxime_Sodium
CHEBI_ID
  • CHEBI:3512
FULL_SYN
  • 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 7-(((2,3-dihydro-2-imino-4-thiazolyl)(methoxyimino)acetyl)amino)-8-oxomonosodium Salt,(6R-(6alpha,7beta(Z)))-SNNCI
  • Ceftizoxime SodiumPTNCI
  • CefizoxBRNCI
  • CEFTIZOXIME SODIUMPTFDA26337D5X88
  • EpocelinSYNCI
DEFINITION
  • The sodium salt form of ceftizoxime and a semi-synthetic, broad-spectrum, beta-lactamase resistant, third-generation cephalosporin antibiotic with bactericidal activity. Ceftizoxime sodium inhibits bacterial cell wall synthesis by inactivating penicillin binding proteins (PBPs) thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of the cell wall. Lack of cross-linking results in a reduction of cell wall stability and leads to cell lysis.NCI
code
  • C47438
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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