About: Peripheral Blood Lymphocyte Vaccine

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Attributes	Values
rdf:type	Class
rdfs:label	Peripheral Blood Lymphocyte Vaccine
rdfs:subClassOf	Cancer Vaccines
Semantic_Type	Pharmacologic Substance Immunologic Factor
Preferred_Name	Peripheral Blood Lymphocyte Vaccine
UMLS_CUI	C1518998
Legacy_Concept_Name	Peripheral_Blood_Lymphocyte_Vaccine
FULL_SYN	Peripheral Blood Lymphocyte VaccinePTNCI
DEFINITION	A class of vaccines with potential antineoplastic activity. Peripheral blood lymphocytes (PBL) are first harvested from a cancer patient and induced to express a particular tumor-associated antigen or multiple antigens. Autologous vaccination with activated PBL may stimulate the host immune system to produce antibodies and/or mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for the antigen(s), resulting in decreased tumor growth. (NCI04)NCI
code	C2841
is rdf:first of	nodeID://b739069
is rdfs:subClassOf of	gp100-Pulsed Peripheral Blood Mononuclear Cell gp100-Reactive Autologous Peripheral Blood Lymphocyte Renal Tumor-Reactive Autologous Peripheral Blood Lymphocyte ESO-1 Reactive Autologous Peripheral Blood Lymphocyte Autologous Anti-MART-1 F5 T-Cell Receptor Gene-Engineered Peripheral Blood Lymphocytes Anti-p53 T-Cell Receptor-Transduced Peripheral Blood Lymphocytes Autologous Anti-gp100:154-162 T-Cell Receptor Gene-Engineered Peripheral Blood Lymphocytes Anti-CEA TCR Retroviral Vector-Transduced Autologous Peripheral Blood Lymphocytes

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