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AttributesValues
rdf:type
rdfs:label
  • Lanreotide
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Lanreotide
PubMedID_Primary_Reference
  • 9641549
UMLS_CUI
  • C0209211
CAS_Registry
  • 108736-35-2
FDA_UNII_Code
  • 0G3DE8943Y
Contributing_Source
  • FDA
Chemical_Formula
  • C54H69N11O10S2
Legacy_Concept_Name
  • Lanreotide
FULL_SYN
  • AngiopeptinFBNCI
  • AngiopeptinBRNCI
  • DermopeptinFBNCI
  • LanreotidePTDCP20381
  • L-Threoninamide, 3-(2-naphthalenyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-, cyclic (2-7)-disulfideSNNCI
  • IpstylFBNCI
  • DC 13116CNNCI
  • LANREOTIDEPTFDA0G3DE8943Y
  • BIM-23014CNNCI
  • Nal-cyclo(cys-tyr-trp-lys-val-cys)-thr-NH2SNNCI
  • LanreotidePTNCI
  • SomatulinaFBNCI
  • SomatulineFBNCI
DEFINITION
  • A synthetic cyclic octapeptide analogue of somatostatin. Lanreotide binds to somatostatin receptors (SSTR), specifically SSTR-2 and also to SSTR-5 with a lesser affinity. However, compare with octreotide, this agent is less potent in inhibiting the release of growth hormone from the pituitary gland. Furthermore, lanreotide has an acute effect on decreasing circulating total and free insulin-like growth factor 1 (IGF-I). This agent is usually given as a prolonged-release microparticle or Autogel formulation for the treatment of acromegaly and to relieve the symptoms of neuroendocrine tumors.NCI
code
  • C1523
sameAs
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