About: Lanreotide Acetate     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Lanreotide Acetate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Lanreotide Acetate
PubMedID_Primary_Reference
  • 9641549
UMLS_CUI
  • C1310656
CAS_Registry
  • 127984-74-1
FDA_UNII_Code
  • IEU56G3J9C
Contributing_Source
  • FDA
Chemical_Formula
  • C54H69N11O10S2.C2H4O2
Legacy_Concept_Name
  • Lanreotide_Acetate
FULL_SYN
  • Somatuline DepotBRNCI
  • AT-1001CNNCI
  • Lanreotide AcetatePTNCI
  • LANREOTIDE ACETATEPTFDAIEU56G3J9C
  • L-Threoninamide, 3-(2-naphthalenyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-, cyclic (2-7)-disulfide, acetateSNNCI
DEFINITION
  • The acetate salt of a synthetic cyclic octapeptide analogue of somatostatin. Lanreotide binds to somatostatin receptors (SSTR), specifically SSTR-2 and also to SSTR-5 with a lesser affinity. However, compare with octreotide, this agent is less potent in inhibiting the release of growth hormone from the pituitary gland. Furthermore, lanreotide has an acute effect on decreasing circulating total and free insulin-like growth factor 1 (IGF-I). This agent is usually given as a prolonged-release microparticle or Autogel formulation for the treatment of acromegaly and to relieve the symptoms of neuroendocrine tumors.NCI
code
  • C74584
sameAs
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