About: Human DNA adducts of 1,3 - butadiene, an important environmental carcinogen.

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About: Human DNA adducts of 1,3 - butadiene, an important environmental carcinogen. Goto Sponge Distinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The N-1-(2,3,4-trihydroxybutyl)adenine (N-1-THB-Ade) adducts induced by 1,3 - butadiene (BD) were analysed from lymphocytes of 15 workers occupationally exposed to BD and 11 controls by 32P-post -labelling usin HPLC with radioactivity detection. Thiss study shows the first time BD - induced DNA adducts in humans and suggests that N-1-THB-Ade adducts may be used to biomonitor human exposure to BD. The N-1-(2,3,4-trihydroxybutyl)adenine (N-1-THB-Ade) adducts induced by 1,3 - butadiene (BD) were analysed from lymphocytes of 15 workers occupationally exposed to BD and 11 controls by 32P-post -labelling usin HPLC with radioactivity detection. Thiss study shows the first time BD - induced DNA adducts in humans and suggests that N-1-THB-Ade adducts may be used to biomonitor human exposure to BD. (en)
Title	Human DNA adducts of 1,3 - butadiene, an important environmental carcinogen. Human DNA adducts of 1,3 - butadiene, an important environmental carcinogen. (en)
skos:prefLabel	Human DNA adducts of 1,3 - butadiene, an important environmental carcinogen. Human DNA adducts of 1,3 - butadiene, an important environmental carcinogen. (en)
skos:notation	RIV/68378041:_____/00:19003074!RIV/2003/AV0/A19003/N
http://linked.open.../vavai/riv/strany	107;111
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(KSK2039602), Z(AV0Z5039906), Z(MSM 111200001)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2003
http://linked.open...aciTvurceVysledku	Šrám, Radim Vodička, Pavel
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální medicíny AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	712856
http://linked.open...ai/riv/idVysledku	RIV/68378041:_____/00:19003074
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	N/A (en)
http://linked.open.../riv/klicoveSlovo	N/A
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[2426EA28CC68]
http://linked.open...i/riv/nazevZdroje	Carcinogenesis
http://linked.open...in/vavai/riv/obor	FM
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Molecular and cellular principles of serious diseases
http://linked.open...UplatneniVysledku	2000
http://linked.open...v/svazekPeriodika	21
http://linked.open...iv/tvurceVysledku	Hemminki, K. Vodička, Pavel Šrám, Radim Jan Zhao, Ch.
http://linked.open...n/vavai/riv/zamer	The molecular and cellular basis of selected human diseases, mechanisms of normal and pathological function, principles of diagnosis and therapy http://linked.opendata.cz/resource/domain/vavai/zamer/MSM%20111200001
issn	0143-3334
number of pages	5 (xsd:int)

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