About: Porcine insulin receptor substrate 4 (IRS4) gene: cloning, polymorphism and association study

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Using PCR and inverse PCR techniques we obtained a 4,498 bp nucleotide sequence FN424076 encompassing the complete coding sequence of the porcine insulin receptor substrate 4 (IRS4) gene and its proximal promoter. The 1,269 amino acid porcine protein deduced from the nucleotide sequence shares 92% identity with the human IRS4 and possesses the same domains and the same number of tyrosine phosphorylation motifs as the human protein. We detected substitution FN424076:g.96C<G in the promoter region that segregates in Meishan and a synonymous substitution FN424076:g.1829T<C in the coding sequence with allele C present only in Meishan. Using PCR and inverse PCR techniques we obtained a 4,498 bp nucleotide sequence FN424076 encompassing the complete coding sequence of the porcine insulin receptor substrate 4 (IRS4) gene and its proximal promoter. The 1,269 amino acid porcine protein deduced from the nucleotide sequence shares 92% identity with the human IRS4 and possesses the same domains and the same number of tyrosine phosphorylation motifs as the human protein. We detected substitution FN424076:g.96C<G in the promoter region that segregates in Meishan and a synonymous substitution FN424076:g.1829T<C in the coding sequence with allele C present only in Meishan. (en)
Title	Porcine insulin receptor substrate 4 (IRS4) gene: cloning, polymorphism and association study Porcine insulin receptor substrate 4 (IRS4) gene: cloning, polymorphism and association study (en)
skos:prefLabel	Porcine insulin receptor substrate 4 (IRS4) gene: cloning, polymorphism and association study Porcine insulin receptor substrate 4 (IRS4) gene: cloning, polymorphism and association study (en)
skos:notation	RIV/67985904:_____/10:00353420!RIV12-AV0-67985904
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA523/07/0353), P(GAP502/10/1216), Z(AV0Z50450515)
http://linked.open...iv/cisloPeriodika	-
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Knoll, Aleš Masopust, Martin Čepica, Stanislav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav živočišné fyziologie a genetiky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	279894
http://linked.open...ai/riv/idVysledku	RIV/67985904:_____/10:00353420
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	PCR cloning; Polymorphism; IRS4 (en)
http://linked.open.../riv/klicoveSlovo	Polymorphism IRS4 PCR cloning
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[9D5BE5087A10]
http://linked.open...i/riv/nazevZdroje	Molecular Biology Reports
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...vavai/riv/projekt	Fine association mapping of the porcine chromosome 2q region influencing meat quality and study of positional candidate genes A study of chromosome regions and genes affecting fat accretion in pigs
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	38
http://linked.open...iv/tvurceVysledku	Knoll, Aleš Bartenschlager, H. Čepica, Stanislav Masopust, Martin Rohrer, G. A. Deeb, N. Mileham, A. Vykoukalová, Z.
http://linked.open...ain/vavai/riv/wos	000289257100050
http://linked.open...n/vavai/riv/zamer	Genetic, functional and developmental potential of animal cells, tissues and organisms: their use in medicine, ecology and agriculture
issn	0301-4851
number of pages	7 (xsd:int)
http://bibframe.org/vocab/doi	10.1007/s11033-010-0402-x
is http://linked.open...avai/riv/vysledek of	Porcine insulin receptor substrate 4 (IRS4) gene: cloning, polymorphism and association study Porcine insulin receptor substrate 4 (IRS4) gene: cloning, polymorphism and association study

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