About: FGF-2 abnormalities in B cell chronic lymphotic and chronic myeloid leukemias.

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About: FGF-2 abnormalities in B cell chronic lymphotic and chronic myeloid leukemias. Goto Sponge Distinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	FGF-2 abnormalities in B cell chronic lymphotic and chronic myeloid leukemias.We conclude that B-CLL WBCs secrete FGF-2 with no apparent autocrine actions. In contrast, WBCs in CML bind FGF-2 provided by other FGF-2-hyperproducing cells and activate the MEK/ERK kinase cascade, possibly to modulate cell growth. FGF-2 abnormalities in B cell chronic lymphotic and chronic myeloid leukemias.We conclude that B-CLL WBCs secrete FGF-2 with no apparent autocrine actions. In contrast, WBCs in CML bind FGF-2 provided by other FGF-2-hyperproducing cells and activate the MEK/ERK kinase cascade, possibly to modulate cell growth. (en)
Title	FGF-2 abnormalities in B cell chronic lymphotic and chronic myeloid leukemias. FGF-2 abnormalities in B cell chronic lymphotic and chronic myeloid leukemias. (en)
skos:prefLabel	FGF-2 abnormalities in B cell chronic lymphotic and chronic myeloid leukemias. FGF-2 abnormalities in B cell chronic lymphotic and chronic myeloid leukemias. (en)
skos:notation	RIV/67985904:_____/01:21010009!RIV/2003/AV0/A21003/N
http://linked.open.../vavai/riv/strany	228;237
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA312/97/0393), P(VS96115), Z(AV0Z5045916)
http://linked.open...iv/cisloPeriodika	N/A
http://linked.open...vai/riv/dodaniDat	2003
http://linked.open...aciTvurceVysledku	Hampl, Aleš Dvořák, Petr
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav živočišné fyziologie a genetiky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	680358
http://linked.open...ai/riv/idVysledku	RIV/67985904:_____/01:21010009
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	leukemia; - FGF-2 (en)
http://linked.open.../riv/klicoveSlovo	- FGF-2 leukemia
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[E93AA492219E]
http://linked.open...i/riv/nazevZdroje	Leukemia
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	The expression of basic fibroblast growth factor (FGF-2) and FGF-receptors in human leukemic cells. Potential use for the monitoring of cancer therapy Molecular embryology -one of the keys for healthy offsprings
http://linked.open...UplatneniVysledku	2001
http://linked.open...v/svazekPeriodika	15
http://linked.open...iv/tvurceVysledku	Dvořák, Petr Dvořáková, D. Hampl, Aleš Mayer, J. Krejčí, P. Pacherník, J. Krahulcová, E.
http://linked.open...n/vavai/riv/zamer	Základní výzkum genetických struktur, fyziologických funkcí a vývojové biologie obratlovců se zaměřením na biomedicínsky, hospodářsky i jinak významné druhy
issn	0887-6924
number of pages	9 (xsd:int)

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