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Description
| - Successfull completion of all developmental processes including gametogenesis, conception, early embryogenesis, establishing the first differentiated cell lineages, morphogenesis, organogenesis, and others, is prerequisite of borning a healthy individual in all living organisms. Any kind of damage to those processes may result in an abortion, malformed offspring, or even in the transfer of DNA damage onto viable and fertile offsprings that may become fixed in population. The detailed knowledge of the molecular basis of developmental processes is critical for actively eliminating those risks. This project addresses two important molecular processes that take place during the early development in mammals, using mice as an model organism. Those processes are: 1)molecular interactions that drive differentiation of the mammalian totipotent stem cells - embryonic induction, (en)
- v CEPu neuvedena
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Title
| - Molecular embryology -one of the keys for healthy offsprings (en)
- Molekulární embryologie - jeden z klíčů ke zdravému potomstvu
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skos:notation
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http://linked.open...avai/cep/aktivita
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http://linked.open...kovaStatniPodpora
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http://linked.open...ep/celkoveNaklady
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http://linked.open...ep/duvernostUdaju
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http://linked.open.../cep/fazeProjektu
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http://linked.open...ai/cep/hlavniObor
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http://linked.open...hodnoceniProjektu
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http://linked.open.../cep/klicovaSlova
| - mouse, early development, embryonic stem cell, fibroblast growth factor, DNA damage (en)
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http://linked.open...ep/partnetrHlavni
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http://linked.open...inujicichPrijemcu
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http://linked.open...cep/pocetPrijemcu
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http://linked.open...ocetSpoluPrijemcu
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http://linked.open.../pocetVysledkuRIV
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http://linked.open...enychVysledkuVRIV
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http://linked.open...iciPoslednihoRoku
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http://linked.open...atUdajeProjZameru
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http://linked.open...usZobrazovaneFaze
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http://linked.open...ai/cep/typPojektu
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http://linked.open.../cep/vedlejsiObor
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http://linked.open...jektu+dodavatelem
| - Laboratoře molekulární embryologie je orientována na studium molekulárních mechanismů, které regulují proliferaci a diferenciaci buněk ve vývoji a v nemoci. (cs)
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http://linked.open...tniCyklusProjektu
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http://linked.open.../cep/klicoveSlovo
| - mouse
- fibroblast growth factor
- early development
- embryonic stem cell
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is http://linked.open...vavai/riv/projekt
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is http://linked.open...vavai/cep/projekt
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