About: Relative deficiency of nitric oxide-dependent vasodilation in salt hypertensive Dahl rats: the possible role of superoxide anions.

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About: Relative deficiency of nitric oxide-dependent vasodilation in salt hypertensive Dahl rats: the possible role of superoxide anions. Goto Sponge Distinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The contribution of major vasoactive systems (renin-angiotensin system, sympathetic nervous system and nitric oxide) to blood pressure maintenance and the possible involvement of superoxide anions in the reduced efficiency of NO-dependent vasodilation to counterbalance sympathetic vasoconstriction were studied in salt hypertensive Dahl rats. It was demonstrated that NO system is not able to counterbalance effectively the hyperactivity of sympathetic nervous system in salt hypertensive Dahl rats. The predominance of sympathetic vasoconstriction over NO-dependent vasodilation could partially be explained by enhanced NO inactivation due to augmented superoxide anion formation in hypertensive animals. The contribution of major vasoactive systems (renin-angiotensin system, sympathetic nervous system and nitric oxide) to blood pressure maintenance and the possible involvement of superoxide anions in the reduced efficiency of NO-dependent vasodilation to counterbalance sympathetic vasoconstriction were studied in salt hypertensive Dahl rats. It was demonstrated that NO system is not able to counterbalance effectively the hyperactivity of sympathetic nervous system in salt hypertensive Dahl rats. The predominance of sympathetic vasoconstriction over NO-dependent vasodilation could partially be explained by enhanced NO inactivation due to augmented superoxide anion formation in hypertensive animals. (en)
Title	Relative deficiency of nitric oxide-dependent vasodilation in salt hypertensive Dahl rats: the possible role of superoxide anions. Relative deficiency of nitric oxide-dependent vasodilation in salt hypertensive Dahl rats: the possible role of superoxide anions. (en)
skos:prefLabel	Relative deficiency of nitric oxide-dependent vasodilation in salt hypertensive Dahl rats: the possible role of superoxide anions. Relative deficiency of nitric oxide-dependent vasodilation in salt hypertensive Dahl rats: the possible role of superoxide anions. (en)
skos:notation	RIV/67985823:_____/01:20010173!RIV/2003/AV0/A20003/N
http://linked.open.../vavai/riv/strany	247;254
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(IAA7011711), P(IAA7011805), Z(AV0Z5011922)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2003
http://linked.open...aciTvurceVysledku	Zicha, Josef Kuneš, Jaroslav Dobešová, Zdeňka
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fyziologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	694430
http://linked.open...ai/riv/idVysledku	RIV/67985823:_____/01:20010173
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	blood pressure; - salt hypertension; - Dahl rats (en)
http://linked.open.../riv/klicoveSlovo	blood pressure - Dahl rats - salt hypertension
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[EEC85AFC3D18]
http://linked.open...i/riv/nazevZdroje	Journal of Hypertension
http://linked.open...in/vavai/riv/obor	FA
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Hypertension and Metabolic Syndrome: causes and consequences Oxygen free radicals and nitric oxide in the pathogenesis of age-dependent experimental hypertension: the attenuation of vasodilator mechanisms ...
http://linked.open...UplatneniVysledku	2001
http://linked.open...v/svazekPeriodika	19
http://linked.open...iv/tvurceVysledku	Kuneš, Jaroslav Zicha, Josef Dobešová, Zdeňka
http://linked.open...n/vavai/riv/zamer	Investigation of normal and pathological physiology of animals - the clarification of the physiological mechanisms operating in humans in health and disease
issn	0263-6352
number of pages	8 (xsd:int)

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