About: Synthesis of novel carbocyclic nucleoside analogues derived from 2-(hydroxymethyl)bicyclo[2.2.1]heptane

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About: Synthesis of novel carbocyclic nucleoside analogues derived from 2-(hydroxymethyl)bicyclo[2.2.1]heptane Goto Sponge Distinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Novel racemic carbocyclic nucleoside analogues of thymine and 6-substituted purines derived from (1R,2R,4R,6R)-6- and (1R,2R,4R,5S)-5-(hydroxymethyl)bicyclo[2.2.1]heptane-2-methanols were synthesized. The target compounds were tested for anti-viral activity. Novel racemic carbocyclic nucleoside analogues of thymine and 6-substituted purines derived from (1R,2R,4R,6R)-6- and (1R,2R,4R,5S)-5-(hydroxymethyl)bicyclo[2.2.1]heptane-2-methanols were synthesized. The target compounds were tested for anti-viral activity. (en) Byla syntetizována nová racemická karbocyklická analoga nukleosidů thyminu a 6-substituovaných purinů odvozená od (1R,2R,4R,6R)-6- a(1R,2R,4R,5S)-5-(hydroxymethyl)bicyklo[2.2.1]heptan-2-methanolů. Cílové látky byly testovány na protivirovou aktivitu. (cs)
Title	Synthesis of novel carbocyclic nucleoside analogues derived from 2-(hydroxymethyl)bicyclo[2.2.1]heptane Synthesis of novel carbocyclic nucleoside analogues derived from 2-(hydroxymethyl)bicyclo[2.2.1]heptane (en) Syntéza nových karbocyklických analog nukleosidů odvozených od 2-(hydroxymethyl)bicyklo[2.2.1]heptanu (cs)
skos:prefLabel	Synthesis of novel carbocyclic nucleoside analogues derived from 2-(hydroxymethyl)bicyclo[2.2.1]heptane Synthesis of novel carbocyclic nucleoside analogues derived from 2-(hydroxymethyl)bicyclo[2.2.1]heptane (en) Syntéza nových karbocyklických analog nukleosidů odvozených od 2-(hydroxymethyl)bicyklo[2.2.1]heptanu (cs)
skos:notation	RIV/61388963:_____/07:00096732!RIV08-AV0-61388963
http://linked.open.../vavai/riv/strany	1523;1544
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1M0508), P(1QS400550501), P(GA203/05/0132), Z(AV0Z40550506)
http://linked.open...iv/cisloPeriodika	11
http://linked.open...vai/riv/dodaniDat	2008
http://linked.open...aciTvurceVysledku	Holý, Antonín Dračínský, Martin Hřebabecký, Hubert Dejmek, Milan
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav organické chemie a biochemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	453939
http://linked.open...ai/riv/idVysledku	RIV/61388963:_____/07:00096732
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	carbocyclic nucleosides; purines; thymine (en)
http://linked.open.../riv/klicoveSlovo	carbocyclic nucleosides purines thymine
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[46A848A45CF0]
http://linked.open...i/riv/nazevZdroje	Collection of Czechoslovak Chemical Communications
http://linked.open...in/vavai/riv/obor	CC
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	New Antivirals and Antineoplastics Novel antivirals and antineoplastics Carbocyclic nucleoside analogues containing substituted norbornanes: compounds with potential biological effects
http://linked.open...UplatneniVysledku	2007
http://linked.open...v/svazekPeriodika	72
http://linked.open...iv/tvurceVysledku	Dračínský, Martin Dejmek, Milan Holý, Antonín Hřebabecký, Hubert
http://linked.open...n/vavai/riv/zamer	Regulace biologických procesů: Chemické modulátory vybraných systémů významných pro medicínu a zemědělství
issn	0010-0765
number of pages	22 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Synthesis of novel carbocyclic nucleoside analogues derived from 2-(hydroxymethyl)bicyclo[2.2.1]heptane Synthesis of novel carbocyclic nucleoside analogues derived from 2-(hydroxymethyl)bicyclo[2.2.1]heptane Synthesis of novel carbocyclic nucleoside analogues derived from 2-(hydroxymethyl)bicyclo[2.2.1]heptane

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