About: Specific in vitro cleavage of Mason-Pfizer monkey virus capsid protein: evidence for a potential role of retroviral protease in early stages of infection.

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About: Specific in vitro cleavage of Mason-Pfizer monkey virus capsid protein: evidence for a potential role of retroviral protease in early stages of infection. Goto Sponge Distinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	We show here that capsid protein (CA) of Mason-Pfizer monkey virus (M-PMV) is cleaved in vitro by the protease within the major homology region (MHR), and nucleocapsid protein in several sites at the N-terminus. The CA cleavage product was also identified shortly after penetration of M-PMV into COS cells, suggesting that protease-catalyzed cleavage is involved in core disintegration. We show here that capsid protein (CA) of Mason-Pfizer monkey virus (M-PMV) is cleaved in vitro by the protease within the major homology region (MHR), and nucleocapsid protein in several sites at the N-terminus. The CA cleavage product was also identified shortly after penetration of M-PMV into COS cells, suggesting that protease-catalyzed cleavage is involved in core disintegration. (en)
Title	Specific in vitro cleavage of Mason-Pfizer monkey virus capsid protein: evidence for a potential role of retroviral protease in early stages of infection. Specific in vitro cleavage of Mason-Pfizer monkey virus capsid protein: evidence for a potential role of retroviral protease in early stages of infection. (en)
skos:prefLabel	Specific in vitro cleavage of Mason-Pfizer monkey virus capsid protein: evidence for a potential role of retroviral protease in early stages of infection. Specific in vitro cleavage of Mason-Pfizer monkey virus capsid protein: evidence for a potential role of retroviral protease in early stages of infection. (en)
skos:notation	RIV/61388963:_____/03:57030099!RIV/2004/GA0/A57004/N
http://linked.open.../vavai/riv/strany	310;318
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA203/00/1241), P(IAB4055202), P(LN00A079), Z(AV0Z4055905)
http://linked.open...iv/cisloPeriodika	N/A
http://linked.open...vai/riv/dodaniDat	2004
http://linked.open...aciTvurceVysledku	Pichová, Iva Rumlová, Michaela
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav organické chemie a biochemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	628086
http://linked.open...ai/riv/idVysledku	RIV/61388963:_____/03:57030099
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	M-PMV protease; HIV-1 capsid protein; HIV-1 protease (en)
http://linked.open.../riv/klicoveSlovo	M-PMV protease HIV-1 capsid protein HIV-1 protease
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[8AD7476AA1C6]
http://linked.open...i/riv/nazevZdroje	Virology
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Center of Integrated Genomics Biological and structural studies of Mason-Pfizer monkey virus protease Study of inhibition of multimerization of retroviral capsid protein from HIV-1
http://linked.open...UplatneniVysledku	2003
http://linked.open...v/svazekPeriodika	310
http://linked.open...iv/tvurceVysledku	Pichová, Iva Ruml, T. Rumlová, Michaela Pohl, J.
http://linked.open...n/vavai/riv/zamer	Chemical principles of selected biological phenomena in medicine and ecology
issn	0042-6822
number of pages	9 (xsd:int)

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