About: Analysis of oxidized phospholipids by MALDI mass spectrometry using 6-Aza-2-thiothymine together with matrix aditives and dsposable trget srfaces

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Analysis of oxidized phospholipids by MALDI mass spectrometry using 6-Aza-2-thiothymine together with matrix aditives and dsposable trget srfaces Goto Sponge Distinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	6-Aza-2-thiothymine (An) is introduced as novel matrix system for the analysis of oxidized phospholipids (OxPLs) by matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS). A systematic evaluation comparing different established and novel matrix substances, especially 2,4,6-THAP matrix (Stubiger, G.; Belgacem O. Anal. Chem. 2007, 79, 3206-3213) as reference compound for phospholipid analysis, and specific matrix additives was performed. Thereby, ATT turned out to be the reagent of choice for MALDI analysis of major biologically relevant OxPL classes (e.g., OxPC, OxPE, and OxPS) in positive and negative ionization mode. ATT used together with specific chaotropic reagents at low concentration (0.5-2 mM) acting as OxPL ionization enhancers revealed an excellent comatrix system for application with MALDI instrument types employing UV- and Nd:YAG laser systems (337 and 355 nm). Moreover, disposable MALDI targets surfaces with specific physicochemical properties (e.g., metallized glass or p 6-Aza-2-thiothymine (An) is introduced as novel matrix system for the analysis of oxidized phospholipids (OxPLs) by matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS). A systematic evaluation comparing different established and novel matrix substances, especially 2,4,6-THAP matrix (Stubiger, G.; Belgacem O. Anal. Chem. 2007, 79, 3206-3213) as reference compound for phospholipid analysis, and specific matrix additives was performed. Thereby, ATT turned out to be the reagent of choice for MALDI analysis of major biologically relevant OxPL classes (e.g., OxPC, OxPE, and OxPS) in positive and negative ionization mode. ATT used together with specific chaotropic reagents at low concentration (0.5-2 mM) acting as OxPL ionization enhancers revealed an excellent comatrix system for application with MALDI instrument types employing UV- and Nd:YAG laser systems (337 and 355 nm). Moreover, disposable MALDI targets surfaces with specific physicochemical properties (e.g., metallized glass or p (en)
Title	Analysis of oxidized phospholipids by MALDI mass spectrometry using 6-Aza-2-thiothymine together with matrix aditives and dsposable trget srfaces Analysis of oxidized phospholipids by MALDI mass spectrometry using 6-Aza-2-thiothymine together with matrix aditives and dsposable trget srfaces (en)
skos:prefLabel	Analysis of oxidized phospholipids by MALDI mass spectrometry using 6-Aza-2-thiothymine together with matrix aditives and dsposable trget srfaces Analysis of oxidized phospholipids by MALDI mass spectrometry using 6-Aza-2-thiothymine together with matrix aditives and dsposable trget srfaces (en)
skos:notation	RIV/60162694:G44__/10:00002365!RIV11-MO0-G44_____
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(MO0FVZ0000501)
http://linked.open...iv/cisloPeriodika	13
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Řehulka, Pavel
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ministerstvo obrany / Univerzita obrany - Fakulta vojenského zdravotnictví Hradec Králové
http://linked.open...dnocenehoVysledku	246434
http://linked.open...ai/riv/idVysledku	RIV/60162694:G44__/10:00002365
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	lipidomics; oxidized phospholipids (OxPLs); lyso-phosphatidylcholine (LPC); 6-aza-2-thiothymine (ATT); diammonium hydrogen citrate (DAHC); chaotropic reagents; disposable MALDI sample targets; MALDI-(TOF/TOF)-MS (en)
http://linked.open.../riv/klicoveSlovo	lipidomics 6-aza-2-thiothymine (ATT) MALDI-(TOF/TOF)-MS chaotropic reagents diammonium hydrogen citrate (DAHC) disposable MALDI sample targets lyso-phosphatidylcholine (LPC) oxidized phospholipids (OxPLs)
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[A4160D916BC1]
http://linked.open...i/riv/nazevZdroje	Analytical Chemistry
http://linked.open...in/vavai/riv/obor	KA
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	82
http://linked.open...iv/tvurceVysledku	Řehulka, Pavel Belgacem, Omar Bicker, Wolfgang Binder, Bernd R. Bochkov, Valery Stuebiger, Gerald
http://linked.open...ain/vavai/riv/wos	000279253300017
http://linked.open...n/vavai/riv/zamer	Zdravotnická problematika ZHN
issn	0003-2700
number of pages	9 (xsd:int)
http://localhost/t...ganizacniJednotka	G44
is http://linked.open...avai/riv/vysledek of	Analysis of oxidized phospholipids by MALDI mass spectrometry using 6-Aza-2-thiothymine together with matrix aditives and dsposable trget srfaces

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 118 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software