About: A comparison of neuroprotective efficacy of the oxime K203 and its fluorinated analogue (KR-22836) with obidoxime in tabun-poisoned rats     Goto   Sponge   Distinct   Permalink

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  • While the ability to reduce tabun-induced acute neurotoxicity of obidoxime and K203 was similar, the neuroprotective efficacy of KR-22836 was slightly higher. Thus, the newly developed fluorinated analogue of K203, called KR-22836, is able to slightly increase the neuroprotective effectiveness of antidotal treatment of acute tabun poisonings compared to K203 and currently available obidoxime
  • While the ability to reduce tabun-induced acute neurotoxicity of obidoxime and K203 was similar, the neuroprotective efficacy of KR-22836 was slightly higher. Thus, the newly developed fluorinated analogue of K203, called KR-22836, is able to slightly increase the neuroprotective effectiveness of antidotal treatment of acute tabun poisonings compared to K203 and currently available obidoxime (en)
Title
  • A comparison of neuroprotective efficacy of the oxime K203 and its fluorinated analogue (KR-22836) with obidoxime in tabun-poisoned rats
  • A comparison of neuroprotective efficacy of the oxime K203 and its fluorinated analogue (KR-22836) with obidoxime in tabun-poisoned rats (en)
skos:prefLabel
  • A comparison of neuroprotective efficacy of the oxime K203 and its fluorinated analogue (KR-22836) with obidoxime in tabun-poisoned rats
  • A comparison of neuroprotective efficacy of the oxime K203 and its fluorinated analogue (KR-22836) with obidoxime in tabun-poisoned rats (en)
skos:notation
  • RIV/60162694:G44__/10:00002276!RIV11-MO0-G44_____
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MO0FVZ0000501)
http://linked.open...iv/cisloPeriodika
  • 5
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
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http://linked.open...dnocenehoVysledku
  • 244531
http://linked.open...ai/riv/idVysledku
  • RIV/60162694:G44__/10:00002276
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Functional observatory battery; neurotoxicity; K203; KR-22836; obidoxime; tabun (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [050E00CA9B47]
http://linked.open...i/riv/nazevZdroje
  • Basic & Clinical Pharmacology & Toxicology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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http://linked.open...v/svazekPeriodika
  • 107
http://linked.open...iv/tvurceVysledku
  • Jung, Young-Sik
  • Kassa, Jiří
  • Kuča, Kamil
  • Musílek, Kamil
  • Tesařová, Sandra
  • Žďárová Karasová, Jana
http://linked.open...ain/vavai/riv/wos
  • 000283093100003
http://linked.open...n/vavai/riv/zamer
issn
  • 1742-7835
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http://localhost/t...ganizacniJednotka
  • G44
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