About: Hepatic antioxidant status and hematological parameters in rainbow trout, Oncorhynchus mykiss, after chronic exposure to carbamazepine     Goto   Sponge   Distinct   Permalink

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  • Recently, residual pharmaceuticals are generally recognized as relevant sources of aquatic environmental pollutants. However, the toxicological effects of these contaminants have not been adequately researched. In this study, the chronic toxic effect of carbamazepine (CBZ), an anticonvulsant drug commonly present in surface and ground water, on hepatic antioxidant status and hematological parameters of rainbow trout were investigated. Fish were exposed at sublethal concentrations of CBZ (1.0_g/l, 0.2 mg/l and 2.0 mg/l) for 7, 21 and 42 days. Compared to the control group, fish exposed at higher concentration (0.2 mg/l or 2.0 mg/l) of CBZ showed significantly higher levels of hemoglobin, ammonia and glucose, and significantly higher plasma enzymes activities. During the exposure duration, erythrocyte count, hematocrit,meanerythrocyte hemoglobin,meanerythrocyte volume,meancolor concentration and total protein content in all groups were not significantly different. At the highest test concentration (2.0
  • Recently, residual pharmaceuticals are generally recognized as relevant sources of aquatic environmental pollutants. However, the toxicological effects of these contaminants have not been adequately researched. In this study, the chronic toxic effect of carbamazepine (CBZ), an anticonvulsant drug commonly present in surface and ground water, on hepatic antioxidant status and hematological parameters of rainbow trout were investigated. Fish were exposed at sublethal concentrations of CBZ (1.0_g/l, 0.2 mg/l and 2.0 mg/l) for 7, 21 and 42 days. Compared to the control group, fish exposed at higher concentration (0.2 mg/l or 2.0 mg/l) of CBZ showed significantly higher levels of hemoglobin, ammonia and glucose, and significantly higher plasma enzymes activities. During the exposure duration, erythrocyte count, hematocrit,meanerythrocyte hemoglobin,meanerythrocyte volume,meancolor concentration and total protein content in all groups were not significantly different. At the highest test concentration (2.0 (en)
Title
  • Hepatic antioxidant status and hematological parameters in rainbow trout, Oncorhynchus mykiss, after chronic exposure to carbamazepine
  • Hepatic antioxidant status and hematological parameters in rainbow trout, Oncorhynchus mykiss, after chronic exposure to carbamazepine (en)
skos:prefLabel
  • Hepatic antioxidant status and hematological parameters in rainbow trout, Oncorhynchus mykiss, after chronic exposure to carbamazepine
  • Hepatic antioxidant status and hematological parameters in rainbow trout, Oncorhynchus mykiss, after chronic exposure to carbamazepine (en)
skos:notation
  • RIV/60076658:12520/10:00011393!RIV11-MZP-12520___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(SP/2E7/229/07), Z(MSM6007665809)
http://linked.open...iv/cisloPeriodika
  • 1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
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http://linked.open...dnocenehoVysledku
  • 261395
http://linked.open...ai/riv/idVysledku
  • RIV/60076658:12520/10:00011393
http://linked.open...riv/jazykVysledku
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  • Fish; Liver; Oxidative stress; Blood indices; Residual pharmaceutical (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • IE - Irsko
http://linked.open...ontrolniKodProRIV
  • [A23CB3D80BDD]
http://linked.open...i/riv/nazevZdroje
  • Chemico-biological interactions
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 183
http://linked.open...iv/tvurceVysledku
  • Grabic, Roman
  • Kolářová, Jitka
  • Li, Zhihua
  • Máchová, Jana
  • Randák, Tomáš
  • Velíšek, Josef
  • Žlábek, Vladimír
http://linked.open...ain/vavai/riv/wos
  • 000273864800011
http://linked.open...n/vavai/riv/zamer
issn
  • 0009-2797
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  • 12520
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