About: New PAH derivatives functionalized by cyclic nitrone framework: Synthetic design, anti-proliferative activity and interaction with DNA     Goto   Sponge   Distinct   Permalink

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Description
  • Novel approach to functionalized polycyclic aromatic hydrocarbons (PAHs) is presented. Incorporation of cyclic nitrone framework into the structure of PAHs was studied with respect to their anti-proliferative activities and interaction with double stranded DNA. Theoretical docking studies and UV titration methods were used for preliminary evaluation of binding of new PAH derivatives to DNA structure.
  • Novel approach to functionalized polycyclic aromatic hydrocarbons (PAHs) is presented. Incorporation of cyclic nitrone framework into the structure of PAHs was studied with respect to their anti-proliferative activities and interaction with double stranded DNA. Theoretical docking studies and UV titration methods were used for preliminary evaluation of binding of new PAH derivatives to DNA structure. (en)
Title
  • New PAH derivatives functionalized by cyclic nitrone framework: Synthetic design, anti-proliferative activity and interaction with DNA
  • New PAH derivatives functionalized by cyclic nitrone framework: Synthetic design, anti-proliferative activity and interaction with DNA (en)
skos:prefLabel
  • New PAH derivatives functionalized by cyclic nitrone framework: Synthetic design, anti-proliferative activity and interaction with DNA
  • New PAH derivatives functionalized by cyclic nitrone framework: Synthetic design, anti-proliferative activity and interaction with DNA (en)
skos:notation
  • RIV/00216224:14310/13:00066011!RIV14-MSM-14310___
http://linked.open...avai/predkladatel
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, P(GA203/09/1345), S
http://linked.open...iv/cisloPeriodika
  • 5
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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  • 91643
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14310/13:00066011
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Polycyclic aromatic hydrocarbon (PAH); Nitrones; DNA; Intercalation; Docking (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [4401648AE15D]
http://linked.open...i/riv/nazevZdroje
  • Bioorganic & Medicinal Chemistry
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  • 21
http://linked.open...iv/tvurceVysledku
  • Buchlovič, Marian
  • Potáček, Milan
  • Kříž, Zdeněk
  • Hofr, Ctirad
http://linked.open...ain/vavai/riv/wos
  • 000314689200005
issn
  • 0968-0896
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.bmc.2013.01.004
http://localhost/t...ganizacniJednotka
  • 14310
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