About: Biological half-lives of bromide and sodium in the rat are connected and dependent on the physiological state

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The biological half-life of bromide, as substituting for sodium or chloride, was investigated with the aid of the radionuclide 82Br in lactating and non-lactating female rats as well as in young rats of varying ages. Non-weaned young rats (12 d) had the highest half-life (269 h) and lactating dams the lowest (44 h). The determined values demonstrated that non-weaned young apparently conserve Na, while lactating dams, due to their large food intake, waste Na. The parallel course of the excretion rates of sodium and bromide ions was demonstrated in adult male rats administered simultaneously with 24Na-sodium chloride and 82Br-bromide. These excretion rates were inversely proportional to the magnitude of sodium intake in the animals. The biological half-life of bromide, as substituting for sodium or chloride, was investigated with the aid of the radionuclide 82Br in lactating and non-lactating female rats as well as in young rats of varying ages. Non-weaned young rats (12 d) had the highest half-life (269 h) and lactating dams the lowest (44 h). The determined values demonstrated that non-weaned young apparently conserve Na, while lactating dams, due to their large food intake, waste Na. The parallel course of the excretion rates of sodium and bromide ions was demonstrated in adult male rats administered simultaneously with 24Na-sodium chloride and 82Br-bromide. These excretion rates were inversely proportional to the magnitude of sodium intake in the animals. (en) S pomocí radionuklidu 82Br byl zjišťován biologický poločas bromidu, namísto biologického poločasu sodíku nebo chloridu, u laktujících a nelaktujících samic potkana a u různě starých potkaních mláďat. Nejdelší poločas (269 hodin) byl stanoven u neodstavených (12-denních) mláďat a nejkratší (44 hodin) u laktujících samic. Na dospělých samcích potkana, kterým byly aplikovány souběžně (radioaktivně označené) chlorid 24Na-sodný a 82Br-bromid draselný, byl demonstrován paralelní průběh rychlosti exkrece sodných a bromidových iontů. Tyto rychlosti exkrece byly nepřímo úměrné množství přijatého sodíku u pokusných zvířat. (cs)
Title	Biological half-lives of bromide and sodium in the rat are connected and dependent on the physiological state Biological half-lives of bromide and sodium in the rat are connected and dependent on the physiological state (en) Biological half-lives of bromide and sodium in the rat are connected and dependent on the physiological state (cs)
skos:prefLabel	Biological half-lives of bromide and sodium in the rat are connected and dependent on the physiological state Biological half-lives of bromide and sodium in the rat are connected and dependent on the physiological state (en) Biological half-lives of bromide and sodium in the rat are connected and dependent on the physiological state (cs)
skos:notation	RIV/00216224:14310/03:00019255!RIV09-AV0-14310___
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(AV0Z5011922)
http://linked.open...vai/riv/dodaniDat	2009
http://linked.open...aciTvurceVysledku	Pavelka, Stanislav
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	599865
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/03:00019255
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	biological half-life; bromide; chloride; rat; radionuclides; sodium (en)
http://linked.open.../riv/klicoveSlovo	biological half-life chloride sodium bromide rat radionuclides
http://linked.open...ontrolniKodProRIV	[21A8A6687757]
http://linked.open...v/mistoKonaniAkce	Athens (Greece)
http://linked.open...i/riv/mistoVydani	Athens
http://linked.open...i/riv/nazevZdroje	Trace Elements in Human: New Perspectives (Ermidou-Pollet S., Pollet S., eds.) [IF=n.a.]
http://linked.open...in/vavai/riv/obor	ED
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...UplatneniVysledku	2003
http://linked.open...iv/tvurceVysledku	Vobecký, Miloslav Pavelka, Stanislav Babický, Arnošt
http://linked.open...vavai/riv/typAkce	WRD - Světová
http://linked.open.../riv/zahajeniAkce	2003-01-01 (xsd:date)
http://linked.open...n/vavai/riv/zamer	Investigation of normal and pathological physiology of animals - the clarification of the physiological mechanisms operating in humans in health and disease
number of pages	9 (xsd:int)
http://purl.org/ne...btex#hasPublisher	University of Athens
http://localhost/t...ganizacniJednotka	14310

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