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Description
| - Ellipticine is an antineoplastic agent, which forms covalent DNA adducts mediated by cytochromes P450 and peroxidases. We evaluated the role of hepatic versus extra-hepatic metabolism of ellipticine, using the Hepatic Cytochrome P450 Reductase Null mouse
- Ellipticine is an antineoplastic agent, which forms covalent DNA adducts mediated by cytochromes P450 and peroxidases. We evaluated the role of hepatic versus extra-hepatic metabolism of ellipticine, using the Hepatic Cytochrome P450 Reductase Null mouse (en)
- Ellipticin tvoří kovalentní adukty s DNA, po aktivaci cvytochromy P450 a peroxidasami. Byla porovnána role jaterního a mimojaterního metabolismu použitím s cytochrom P450 reduktaza deficientního myšího modelu. (cs)
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Title
| - Role of hepatic cytochromes P450 in bioactivation of the anticancer drug ellipticine: Studies with the hepatic NADPH: Cytochrome P450 reductase null mouse
- Role jaterních cytochromů P450 při biotransformaci protinádorového léčiva ellipticinu (cs)
- Role of hepatic cytochromes P450 in bioactivation of the anticancer drug ellipticine: Studies with the hepatic NADPH: Cytochrome P450 reductase null mouse (en)
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skos:prefLabel
| - Role of hepatic cytochromes P450 in bioactivation of the anticancer drug ellipticine: Studies with the hepatic NADPH: Cytochrome P450 reductase null mouse
- Role jaterních cytochromů P450 při biotransformaci protinádorového léčiva ellipticinu (cs)
- Role of hepatic cytochromes P450 in bioactivation of the anticancer drug ellipticine: Studies with the hepatic NADPH: Cytochrome P450 reductase null mouse (en)
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skos:notation
| - RIV/00216208:11310/08:13541!RIV09-MSM-11310___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(1M0505), P(GA203/06/0329), Z(MSM0021620808)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11310/08:13541
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - anticancer drug; ellipticine; cytochrome P450; peroxidase; DNA adducts; P-32-postlabelling; dna adduct formation; prostaglandin-h synthase; environmental-pollutant 3-nitrobenzanthrone; metabolic-activation; determines susceptibility; xenobiotic-metabolism; liver-microsomes; oxidation; enzymes; mice (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Toxicology and applied pharmacology
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Hudeček, Jiří
- Stiborová, Marie
- Kotrbová, Věra
- Moserová, Michaela
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http://linked.open...ain/vavai/riv/wos
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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is http://linked.open...avai/riv/vysledek
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