About: Biomarkers demonstrate increased consumption, but not abuse, of ethanol in essential tremor     Goto   Sponge   Distinct   Permalink

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Description
  • Ethanol is known to improve tremor in a proportion of patients with essential tremor. Increased incidence of alcoholism has been suspected in essential tremor patients; however, no objective evaluation has been performed using laboratory markers to date. Data on alcohol intake in the last 30 days were acquired in 95 essential tremor patients and 35 healthy controls. Blood and urine markers related to alcohol metabolism and liver function were evaluated. Self-reported alcohol intake and biomarker levels were higher in essential tremor, but the difference was only significant for carbohydrate-deficient transferrin. None of the subjects presented with laboratory parameters reflecting chronic alcohol abuse. Our data do not reflect a higher incidence of alcoholism in patients with essential tremor. Their alcohol intake is well controlled and does not exceed the limits of healthy social drinking.
  • Ethanol is known to improve tremor in a proportion of patients with essential tremor. Increased incidence of alcoholism has been suspected in essential tremor patients; however, no objective evaluation has been performed using laboratory markers to date. Data on alcohol intake in the last 30 days were acquired in 95 essential tremor patients and 35 healthy controls. Blood and urine markers related to alcohol metabolism and liver function were evaluated. Self-reported alcohol intake and biomarker levels were higher in essential tremor, but the difference was only significant for carbohydrate-deficient transferrin. None of the subjects presented with laboratory parameters reflecting chronic alcohol abuse. Our data do not reflect a higher incidence of alcoholism in patients with essential tremor. Their alcohol intake is well controlled and does not exceed the limits of healthy social drinking. (en)
Title
  • Biomarkers demonstrate increased consumption, but not abuse, of ethanol in essential tremor
  • Biomarkers demonstrate increased consumption, but not abuse, of ethanol in essential tremor (en)
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  • Biomarkers demonstrate increased consumption, but not abuse, of ethanol in essential tremor
  • Biomarkers demonstrate increased consumption, but not abuse, of ethanol in essential tremor (en)
skos:notation
  • RIV/00216208:11110/12:9949!RIV13-MZ0-11110___
http://linked.open...avai/predkladatel
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(NS10336), Z(MSM0021620849)
http://linked.open...iv/cisloPeriodika
  • 6
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 125117
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11110/12:9949
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Essential tremor (ET); alcohol; alcoholism; biomarkers (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV
  • [B3FE972409DF]
http://linked.open...i/riv/nazevZdroje
  • Journal of Neurology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 259
http://linked.open...iv/tvurceVysledku
  • Růžička, Evžen
  • Zima, Tomáš
  • Ulmanová, Olga
  • Vinopalová, Marie
http://linked.open...ain/vavai/riv/wos
  • 000304859300023
http://linked.open...n/vavai/riv/zamer
issn
  • 0340-5354
number of pages
http://localhost/t...ganizacniJednotka
  • 11110
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