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rdf:type
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Description
| - STAT 1 levels and inducibility of its activated phosphoforms were detected by Western analysis using specific polyclonal and monoclonal antibodies. The study demonstrates STAT 1 functional abnormalities in melanoma cells. On the basis of detail analyses of patient melanoma cells with respect to the inducibility of STAT 1 phosphorylation by IFNs, four categories of patients could be distinguished: a) activation on both S 727 and Y 701, b) not inducible response, c) activation on Y 701 but not on S 727, d) heterogeneous response.
- STAT 1 levels and inducibility of its activated phosphoforms were detected by Western analysis using specific polyclonal and monoclonal antibodies. The study demonstrates STAT 1 functional abnormalities in melanoma cells. On the basis of detail analyses of patient melanoma cells with respect to the inducibility of STAT 1 phosphorylation by IFNs, four categories of patients could be distinguished: a) activation on both S 727 and Y 701, b) not inducible response, c) activation on Y 701 but not on S 727, d) heterogeneous response. (en)
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Title
| - Malignant melanoma associates with deficient IFN-induced STAT 1 phosphorylation
- Malignant melanoma associates with deficient IFN-induced STAT 1 phosphorylation (en)
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skos:prefLabel
| - Malignant melanoma associates with deficient IFN-induced STAT 1 phosphorylation
- Malignant melanoma associates with deficient IFN-induced STAT 1 phosphorylation (en)
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skos:notation
| - RIV/00209805:_____/03:00008216!RIV/2004/GA0/L26004/N
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(GA301/00/0564), P(NC7139)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00209805:_____/03:00008216
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - STAT 1;malignant melanoma;signal transduction;interferons (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - International journal of molecular medicine
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Boudný, Vladimír
- Kovařík, Jan
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issn
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number of pages
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