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Namespace Prefixes

PrefixIRI
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n13http://linked.opendata.cz/resource/drugbank/drug/DB00096/identifier/genbank/
n12http://linked.opendata.cz/resource/drugbank/drug/DB00096/identifier/uniprotkb/
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n11http://linked.opendata.cz/resource/drugbank/company/
n20http://linked.opendata.cz/resource/drugbank/dosage/
n21http://linked.opendata.cz/resource/drugbank/drug/DB00096/identifier/wikipedia/
n6http://linked.opendata.cz/resource/drugbank/drug/DB00096/identifier/pharmgkb/
n10http://bio2rdf.org/drugbank:
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n15http://linked.opendata.cz/resource/drugbank/patent/
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owlhttp://www.w3.org/2002/07/owl#
n18http://linked.opendata.cz/ontology/mesh/
n3http://linked.opendata.cz/ontology/drugbank/
n7http://linked.opendata.cz/resource/drugbank/property/
xsdhhttp://www.w3.org/2001/XMLSchema#

Statements

Subject Item
n2:DB00096
rdf:type
n3:Drug
n3:description
A sterile non-pyrogenic suspension of microspheres of human serum albumin with perflutren (a highly fluorinated small molecule) for contrast enhancement during indicated ultrasound imaging procedures.
n3:dosage
n20:271B44F0-363D-11E5-9242-09173F13E4C5
n3:generalReferences
# Zunszain PA, Ghuman J, Komatsu T, Tsuchida E, Curry S: Crystal structural analysis of human serum albumin complexed with hemin and fatty acid. BMC Struct Biol. 2003 Jul 7;3:6. Epub 2003 Jul 7. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/12846933
n3:group
approved
n3:indication
For treatment of severe blood loss, hypervolemia, hypoproteinemia.
n3:manufacturer
n11:271B44EE-363D-11E5-9242-09173F13E4C5
owl:sameAs
n10:DB00096 n14:DB00096
dcterms:title
Serum albumin
adms:identifier
n5:DB00096 n6:PA164749380 n8:0407-2707-03 n12:P02768 n13:M12523 n21:Serum_albumin
n3:mechanismOfAction
Serum albumin acts as a high molecular weight, very soluble osmolyte. Serum albumin also acts as a protein drug carrier in plasma, and transports hemin, steroids, thyroid hormones and fatty acids. It binds many other substances, such as unconjugated bilirubin, calcium ions, and other fat soluble hormones.
n3:packager
n11:271B44EC-363D-11E5-9242-09173F13E4C5 n11:271B44ED-363D-11E5-9242-09173F13E4C5 n11:271B44EA-363D-11E5-9242-09173F13E4C5 n11:271B44EB-363D-11E5-9242-09173F13E4C5
n3:patent
n15:5558094 n15:6723303
n3:synonym
Serum albumin precursor
n3:synthesisReference
Rene Fickat, Simon Benita, Francis Puisieux, "Preparation of biodegradable microcapsules based on serum albumin." U.S. Patent US4666641, issued June, 1958.
n18:hasConcept
n19:M0019692
n3:Molecular-Formula
n7:271B44F5-363D-11E5-9242-09173F13E4C5
n3:Molecular-Weight
n7:271B44F4-363D-11E5-9242-09173F13E4C5
n3:affectedOrganism
Humans and other mammals
n3:casRegistryNumber
9048-49-1
n3:category
n3:containedIn
n16:271B44EF-363D-11E5-9242-09173F13E4C5
n3:Hydrophobicity
n7:271B44F2-363D-11E5-9242-09173F13E4C5
n3:Isoelectric-Point
n7:271B44F3-363D-11E5-9242-09173F13E4C5
n3:Melting-Point
n7:271B44F1-363D-11E5-9242-09173F13E4C5