"Multivitamins/minerals which have vitamins ADEK, folate, or iron: If pancrelipase is used in combination with multivitamins/minerals that have vitamins ADEK, folate, or iron then monitor therapy because pancrelipase may decrease absorption of iron in these multivitamin/mineral products."@en . "approved"@en . . . . "Pancrelipase is not significantly absorbed from the gastrointestinal tract and acts locally, so there is no terminal elimination half life. "@en . . . "PA"@en . . "Pancrelipase is eliminated in the feces. "@en . . . . " "@en . . . . . . . . . . . . . . . . . . "Delayed release capsules should not be broken or crushed, but for those patients who cannot swallow the capsules, sprinkle the contents of the capsule onto soft acidic foods (pH of \u22644.5). Alkaline foods with a higher pH will promote early release of pancrelipase followed by enzyme inactivation in the stomach. "@en . "Take pancrelipase with meals and a sufficient amount of water."@en . . . . "Humans and other mammals"@en . . . . . . . "For treatment of exocrine pancreatic insufficiency in cystic fibrosis (Ultresa\u2122), chronic pancreatitis (Viokace\u2122 in combination with a proton pump inhibitor), and pancreatectomy (Viokace\u2122 in combination with a proton pump inhibitor). "@en . . . . . . . . . "1,4-alpha-D- glucan glucanohydrolase"@en . . . . . . . . . . . . . . . . "The lipase, protease and amylase components of pancrelipase break down fat, protein, and starches, respectively, in the small intestine. Lipase hydrolyzes fats into glycerol and fatty acids. Protease converts proteins into proteoses and derived substances, while amylase converts starches into dextrins and sugars."@en . . . . . "Pancrelipase is not significantly absorbed, so there is minimal clearance from the body."@en . . "Pancrelipase is an enzyme mixture isolated from porcine or bovine pancreas, sometimes called pancreatin. It contains 3 enzymes: amylase, lipase, and a protease (chymotrypsin). Pancrelipase is marketed under several brand names such as Ultresa\u2122 and Viokace\u2122."@en . . . . "Pancreatic alpha-amylase precursor"@en . "Pancrelipase acts locally, so there is no volume of distribution. "@en . "Pancrelipase"@en . . . "Overdose symptoms may include diarrhea or stomach upset. The most common adverse reactions seen are ear, neck, and abdominal pain; headache, nasal congestion, and beta-hemolytic streptococcal infection. "@en . "Pancrelipase acts locally, so there is minimal plasma protein binding. "@en . "53608-75-6"@en . . "Pancrelipase is not significantly absorbed from the gastrointestinal tract."@en . . . . . .