. . . "Binds to the CD20 antigen which is found on mature B lymphocytes. The antibody binding appears to induce apoptosis, complement-dependent cytotoxicity and cell death through ionizing radiation."@en . . "Murine IgG2a lambda monoclonal antibody against CD20 antigen (2 heavy chains of 451 residues, 2 lambda chains of 220 residues). It is produced in an antibiotic-free culture of mammalian cells. It can be covalently linked to Iodine 131 (a radioactive isotope of iodine)."@en . . . . . . . "* 68.2 mg/hr [patients with NHL]"@en . . "For treatment of non-Hodgkin's lymphoma (CD20 positive, follicular)"@en . . . "Humans and other mammals"@en . . "Elimination of Iodine-131 occurs by decay and excretion in the urine."@en . . "Tositumomab"@en . "192391-48-3"@en . . "0.8 hours (mammalian reticulocytes, in vitro)"@en . . . . . . "approved"@en . "Ig gamma-1 chain C region"@en .