"Imiglucerase"@en . "* 14.5 +/- 4.0 mL/min/kg"@en . . "approved"@en . . . . "* 0.09 to 0.15 L/kg"@en . . "143003-46-7"@en . "Humans and other mammals"@en . "3.6-10.4 min"@en . . "Imiglucerase catalyzes the hydrolysis of the glycolipid, glucocerebroside, to glucose and ceramide as part of the normal degradation pathway for membrane lipids."@en . . "# Pastores GM, Hughes DA: Gaucher Disease \"Pubmed\":http://www.ncbi.nlm.nih.gov/pubmed/20301446"@en . . "For the treatment of Gaucher's disease (deficiency in glucocerebrosidase)"@en . . . . . . . . . . . . . . "Human Beta-glucocerebrosidase or Beta-D-glucosyl-N-acylsphingosine glucohydrolase E.C. 3.2.1.45. 497 residue protein with N-linked carbohydrates, MW=59.3 kD. Alglucerase is prepared by modification of the oligosaccharide chains of human Beta-glucocerebrosidase. The modification alters the sugar residues at the non-reducing ends of the oligosaccharide chains of the glycoprotein so that they are predominantly terminated with mannose residues"@en . . . . . " "@en .