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Namespace Prefixes

PrefixIRI
n2http://linked.opendata.cz/resource/drugbank/drug/
dctermshttp://purl.org/dc/terms/
n9http://linked.opendata.cz/resource/drugbank/drug/DB00045/identifier/genbank/
n10http://linked.opendata.cz/resource/drugbank/drug/DB00045/identifier/uniprotkb/
n13http://bio2rdf.org/drugbank:
n12http://linked.opendata.cz/resource/drugbank/drug/DB00045/identifier/pharmgkb/
admshttp://www.w3.org/ns/adms#
n7http://wifo5-03.informatik.uni-mannheim.de/drugbank/resource/drugs/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
owlhttp://www.w3.org/2002/07/owl#
n3http://linked.opendata.cz/ontology/drugbank/
n11http://linked.opendata.cz/resource/drugbank/drug/DB00045/identifier/drugbank/
n4http://linked.opendata.cz/resource/drugbank/property/
xsdhhttp://www.w3.org/2001/XMLSchema#

Statements

Subject Item
n2:DB00045
rdf:type
n3:Drug
n3:description
Vaccine against Lyme disease that contains lipoprotein OspA, an outer surface protein of Borrelia burgdorferi sensu stricto ZS7, as expressed by Escherichia coli. Lipoprotein OspA is a single polypeptide chain of 257 amino acids with lipids covalently bonded to the N terminus. It is conjugated with alum (aluminum hydroxide) as an adjuvant.
n3:group
approved withdrawn
n3:halfLife
1.2 hours (mammalian reticulocytes, in vitro).
n3:indication
For prophylactic treatment of Lyme Disease
owl:sameAs
n7:DB00045 n13:DB00045
dcterms:title
OspA lipoprotein
adms:identifier
n9:X16467 n10:P14013 n11:DB00045 n12:PA164743058
n3:mechanismOfAction
OspA lipoprotein, an outer surface protein of the bacteria Borrelia burgdorferi sensu stricto ZS7, is used to stimulate the production of specific antibodies against B. burgdorferi. It is used as a vaccination against Lyme Disease, a disease carried by ticks.
n3:synonym
Outer surface protein A precursor
n3:Molecular-Formula
n4:271B4173-363D-11E5-9242-09173F13E4C5
n3:Molecular-Weight
n4:271B4172-363D-11E5-9242-09173F13E4C5
n3:affectedOrganism
Humans and other mammals
n3:category
n3:Hydrophobicity
n4:271B4170-363D-11E5-9242-09173F13E4C5
n3:Isoelectric-Point
n4:271B4171-363D-11E5-9242-09173F13E4C5