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Namespace Prefixes

PrefixIRI
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Statements

Subject Item
n2:DB00032
rdf:type
n3:Drug
n3:description
Menotropins contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the urine of postmenopausal women. It is used as a fertility medication that is injected either subcutaneously or intramuscularly. It is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with 2 subunits, alpha = 92 residues, beta=111 residues.
n3:dosage
n7:271B40A5-363D-11E5-9242-09173F13E4C5 n7:271B40A6-363D-11E5-9242-09173F13E4C5 n7:271B40A7-363D-11E5-9242-09173F13E4C5
n3:group
approved
n3:indication
For the treatment of female infertility
owl:sameAs
n16:DB00032 n17:DB00032
dcterms:title
Menotropins
adms:identifier
n9:P01229 n10:X00264 n20:DB00032 n21:PA164749406 n22:Menotropins
n3:mechanismOfAction
Being a combination drug, Menotropins bind to the Follicle stimulating hormone receptor (which results in ovulation in the absence of sufficient endogenous Luteinizing hormone)and It also binds to the LH receptor, thereby stimulating proper hormone release. The drug contains both FSH and LH,therefore, it induces ovarian follicular growth and development as well as gonadal steroid production in women who do not have ovarian failure.FSH is the primary driver of follicular recruitment and growth in early folliculogenesis, while LH is important for ovarian steroidogenesis and is involved in the physiological events leading to development of a competent pre-ovulatory follicle
n3:packager
n24:271B40A1-363D-11E5-9242-09173F13E4C5
n4:hasAHFSCode
n5:68-18-00
n18:hasConcept
n19:M0013384
foaf:page
n12:menotropins.htm n23:menotropins.html
n3:Molecular-Formula
n6:271B40AC-363D-11E5-9242-09173F13E4C5
n3:Molecular-Weight
n6:271B40AB-363D-11E5-9242-09173F13E4C5
n3:affectedOrganism
Humans and other mammals
n3:casRegistryNumber
61489-71-2
n3:category
n3:containedIn
n13:271B40A4-363D-11E5-9242-09173F13E4C5 n13:271B40A2-363D-11E5-9242-09173F13E4C5 n13:271B40A3-363D-11E5-9242-09173F13E4C5
n3:Hydrophobicity
n6:271B40A9-363D-11E5-9242-09173F13E4C5
n3:Isoelectric-Point
n6:271B40AA-363D-11E5-9242-09173F13E4C5
n3:Melting-Point
n6:271B40A8-363D-11E5-9242-09173F13E4C5