. . . . . . . . . . . "The project was designed to explore various aspects related to acute and chronic kidney failure, multiorgan failure, and liver injury. The results have been presented in 736 publications, 2 patent applications, 1license and the construction of a functional model (a device designed to control body temperature). A total of 294 published data have appeared in international prestigious journals with i"@en . "N\u00E1hrada a podpora funkce n\u011Bkter\u00FDch \u017Eivotn\u011B d\u016Fle\u017Eit\u00FDch org\u00E1n\u016F" . . "P\u0159edm\u011Btem v\u00FDzkumn\u00E9 \u010Dinnosti byla n\u00E1hrada a podpora \u017Eivotn\u011B d\u016Fle\u017Eit\u00FDch org\u00E1n\u016F p\u0159i jejich akutn\u00EDm nebo chronick\u00E9m selh\u00E1v\u00E1n\u00ED (ledviny, multiorg\u00E1nov\u00E9 selh\u00E1n\u00ED, posti\u017Een\u00ED jater). V\u00FDsledky byly uplatn\u011Bny v podob\u011B 736 publika\u010Dn\u00ED v\u00FDstup\u016F, 2 patent\u016F, 1 u\u017Eitn\u00E9ho vzoru a konstrukce funk\u010Dn\u00EDho vzorku. 294 publikovan\u00FDch v\u00FDsledk\u016F bylo zve\u0159ejn\u011Bno v mezin\u00E1rodn\u011B respektovan\u00FDch \u010Dasopisech s faktorem impaktu. Z\u00E1v\u011Bre\u010Dn"@cs . "739"^^ . . "2011-01-26+01:00"^^ . "The subject of the research activity implemented within the proposed research plan is the replacement and support of some important organs in case of the failure of their functions. In specific terms, the problemsin connection with renal failure, multiple organ failure and hepatic failure are going to be studied. Ways of how to optimize the use of the existing methods shall be searched for, as well as ways of how to modify the existing methodsin order to achieve their better bioadequacy, and possibilities leading to new methods of the supportive and replacement therapy of failing organs."@en . "Replacement of and support to some vital organs"@en . "2005-01-01+01:00"^^ . . "0"^^ . "renal failure; multiple organ failure; hepatic failure"@en . "P\u0159edm\u011Btem v\u00FDzkumn\u00E9ho z\u00E1m\u011Bru je n\u00E1hrada a podpora n\u011Bkter\u00FDch \u017Eivotn\u011B d\u016Fle\u017Eit\u00FDch org\u00E1n\u016F p\u0159i selh\u00E1v\u00E1n\u00ED jejich funkce. Konkr\u00E9tn\u011B bude zkoum\u00E1na problematika souvisej\u00EDc\u00ED se selh\u00E1n\u00EDm ledvin, s multiorg\u00E1nov\u00FDm selh\u00E1n\u00EDm a se selh\u00E1n\u00EDm jaterC\u00EDlem je bli\u017E\u0161\u00ED pozn\u00E1n\u00ED etiopatogeneze selh\u00E1n\u00ED org\u00E1n\u016F, optimalizace u\u017Eit\u00ED st\u00E1vaj\u00EDc\u00EDch metod n\u00E1hrady a podpory, jejich modifikace k dosa\u017Een\u00ED vy\u0161\u0161\u00ED bioadekv\u00E1tnosti a p\u0159\u00EDprava metod nov\u00FDch.Dal\u0161\u00EDm c\u00EDlem je naj\u00EDt opat\u0159en\u00ED, kter\u00E1 selh\u00E1n\u00ED org\u00E1n\u016F zabr\u00E1n\u00ED nebo je odd\u00E1l\u00ED. Kone\u010Dn\u00FDm c\u00EDlem jesn\u00ED\u017Een\u00ED morbidity a mortality nemocn\u00FDch se selh\u00E1vaj\u00EDc\u00EDmi org\u00E1ny a sn\u00ED\u017Een\u00ED ekonomick\u00FDch n\u00E1klad\u016F na l\u00E9\u010Dbu." . . "1"^^ . "2011-12-31+01:00"^^ . "739"^^ . "2012-08-17+02:00"^^ . . . . . "0"^^ .