"1"^^ . . . . . "The research will be focused on genomics, proteomics, bioinformatics, physiology, stress factors, differentiation, morphology, phylogenesis and ecology of microorganisms including their biodegradation activities and mechanisms of long-term adaptations to adverse conditions. Biotransformations and recombinant and transgenic microbial technologies will also be studied and used to construct recombinant microorganisms, whose products will be obtained on a pilot plant scale. Molecular mechanisms of photosynthetic processes in both algae and bacteria and phototrophic and heterotrophic production of alge will also be studied. Molecular aspects of bacterial pathogenicity and innate and acquired immune response will be analyzed in conventional and germ-free animals. Attention will be paid to their regulation under physiological and pathologically modified conditions (autoimmune diseases, tumors) and new anti-tumor drugs and immunotherapeutics will be investigated."@en . "0"^^ . . . "V\u00FDzkum byl zam\u011B\u0159en na genomiku, proteomiku, bioinformatiku, fyziologii a ekologii mikroorganism\u016F v\u010Detn\u011B jejich biodegrada\u010Dn\u00EDch aktivit. D\u00E1le byly studov\u00E1ny biotransformace, rekombinantn\u00ED a transgenn\u00ED mikrobn\u00ED technologie. Byly analyzov\u00E1ny molekul\u00E1rn\u00ED aspekty bakteri\u00E1ln\u00ED patogenicity a regulace imunitn\u00EDch reakc\u00ED za fyziologick\u00FDch a patologicky zm\u011Bn\u011Bn\u00FDch podm\u00EDnek."@cs . . . "algae; antibiotics; autoimmune diseases; bacteria; bioinformatics; bioremediation; biotechnology; cancer; cell ultrastructure; enzymes; secondary metbolites; fungi; germ-free; immunology; microbiology; molecular biology; nanotechnology; streptomycetes; \u2026"@en . . "The research was focused on the genomics, proteomics, bioinformatics, physiology, and ecology of microorganisms including their biodegradation activities. Biotransformation, recombinant as well as transgenic microbial technologies were studied. Molecular aspects of bacterial pathogenicity and regulation of immune reactions under physiological and pathological conditions were analyzed."@en . "2011-12-06+01:00"^^ . . "2005-01-01+01:00"^^ . . "V\u00FDzkum bude zam\u011B\u0159en na genomiku, proteomiku, bioinformatiku, fyziologii, stresov\u00E9 faktory, diferenciaci, morfologii, fylogenezi a ekologii mikroorganizm\u016F v\u010Detn\u011B jejich biodegrada\u010Dn\u00EDch aktivit a na mechanizmy jejich dlouhodob\u00FDch adaptac\u00ED k nep\u0159\u00EDzniv\u00FDm podm\u00EDnk\u00E1m. D\u00E1le budou studov\u00E1ny biotransformace, rekombinantn\u00ED a transgenn\u00ED mikrobn\u00ED technologie. \u0160lecht\u011Bn\u00EDm a molekul\u00E1rn\u011B genetick\u00FDmi metodami budou p\u0159ipravov\u00E1ny rekombinantn\u00ED mikroorganizmy a v poloprovozn\u00EDch m\u011B\u0159\u00EDtk\u00E1ch z\u00EDsk\u00E1v\u00E1ny jejich produkty. U \u0159as a bakteri\u00ED budou studov\u00E1ny molekul\u00E1rn\u00ED mechanizmy fotosyntetick\u00FDch proces\u016F a fototrofick\u00E1 a heterotrofick\u00E1 reprodukce. Budou analyzov\u00E1ny molekul\u00E1rn\u00ED aspekty bakteri\u00E1ln\u00ED patogenicity, vrozen\u00E9 i z\u00EDskan\u00E9 imunitn\u00ED reakce u konven\u010Dn\u00EDch i bezmikrobn\u00EDch zv\u00ED\u0159at a jejich regulace za fyziologick\u00FDch a patologicky zm\u011Bn\u011Bn\u00FDch podm\u00EDnek. Pozornost bude v\u011Bnov\u00E1na studiu a mo\u017En\u00E9mu ovlivn\u011Bn\u00ED autoimunitn\u00EDch reakc\u00ED a n\u00E1dorov\u00FDch onemocn\u011Bn\u00ED, p\u0159\u00EDprav\u011B vakc\u00EDn, protin\u00E1dorov\u00FDch l\u00E9\u010Div a imunoterapeutik." . . "Microorganisms in Research and Biotechnology"@en . . . "2012-07-03+02:00"^^ . . "2011-12-31+01:00"^^ . . . . "1611"^^ . "0"^^ . "Mikroorganizmy ve v\u00FDzkumu a biotechnologi\u00EDch" . . "1611"^^ .