"IMIDAPRIL HYDROCHLORIDEPTFDA7NSF9GG1NU" . "The hydrochloride salt of imidapril, an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, imidapril is converted by hydrolysis in the liver into its active form imidaprilat. Imidaprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Imidaprilat also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.NCI" . "89396-94-1"^^ . "C20H27N3O6.ClH"^^ . "FDA"^^ . "C99550"^^ . . "(S)-3-(N-((S)-1-Ethoxycarbonyl-3-phenylpropyl)-L-alanyl)-1-methyl-2-oxoimidazoline-4-carboxylic Acid, HydrochlorideSNNCI" . . . "C0872994"^^ . "Imidapril Hydrochloride"^^ . "Imidapril Hydrochloride"^^ . . "7NSF9GG1NU"^^ . "Pharmacologic Substance"^^ . "Imidapril HydrochloridePTNCI" . .