"5-Fluorouracil/Salicylic Acid Topical Solution"^^ . "LAS 41005CNNCI" . . "701314"^^ . "Pharmacologic Substance"^^ . "701314"^^ . "Low-dose 5-Fluorouracil/Salicylic AcidSYNCI" . "ActikerallFBNCI" . "C97131"^^ . "A topical formulation containing 0.5 % of antimetabolite 5-fluorouracil (5-FU) and 10% of salicylic acid, with potential antimitotic and keratolytic activity. Upon cutaneous application, 5-FU in the 5-fluorouracil/salicylic acid topical solution impedes pyrimidine metabolism thereby inhibiting cell growth, while the salicylic acid induces anti-inflammatory response and results in keratolytic effect. This may result in the breakdown of keratinocytes and prevent proliferation of keratinocytes locally.NCI" . "5-Fluorouracil/Salicylic Acid Topical SolutionPTNCI" . "CL429685"^^ . "5-Fluorouracil/Salicylic Acid Topical Solution"^^ . .