. . "Immunologic Factor"^^ . "Iodine I 131 Monoclonal Antibody F16SIP"^^ . "689747"^^ . "CL426559"^^ . "Iodine I 131 Monoclonal Antibody F16SIP"^^ . "131I-F16SIPABNCI" . "Pharmacologic Substance"^^ . "689747"^^ . "TenaradBRNCI" . "(131I) Monoclonal Antibody F16SIPSYNCI" . "Iodine I 131 Monoclonal Antibody F16SIPPTNCI" . "A fully human monoclonal antibody (MoAb) against human A1 domain of tenascin-C, in small immunoprotein (SIP) format conjugated with iodine 131 with potential antineoplastic activity. Iodine I 131 MoAb F16SIP binds to tenascin-C on the vascular tissues and delivers cytotoxic radiation to the tumors, thereby minimizing systemic radiotoxicity. Tenascin-C is a glycoprotein of the extracellular matrix, and the large isoform of this matrix protein is expressed and restricted around vascular structures in the tumor stroma of a variety of different tumors.NCI" . "F16-131IABNCI" . "C95025"^^ .